03371nam 22006495 450 991040969730332120220311130420.0981-15-3532-910.1007/978-981-15-3532-1(CKB)4100000011208574(MiAaPQ)EBC6185889(DE-He213)978-981-15-3532-1(PPN)243764197(EXLCZ)99410000001120857420200422d2020 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierB Cells in Immunity and Tolerance /edited by Ji-Yang Wang1st ed. 2020.Singapore :Springer Singapore :Imprint: Springer,2020.1 online resource (190 pages)Advances in Experimental Medicine and Biology,0065-2598 ;1254981-15-3531-0 B cell development and maturation -- B cell receptor signalling -- Involvement of reactive oxygen species (ROS) in BCR signaling as a second messenger -- Germinal center reaction -- Memory B cells in local and systemic sites -- Regulation of plasma cell differentiation -- Regulation of humoral immune responses and B cell tolerance by the IgM Fc receptor -- Regulatory B cells -- Diversified IgA-bacteria interaction in gut homeostasis -- Primary antibody deficiencies -- B cell-mediated autoimmune diseases -- B cell lymphomas.This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.Advances in Experimental Medicine and Biology,0065-2598 ;1254ImmunologyMolecular biologyAllergyImmunologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B14000Molecular Medicinehttps://scigraph.springernature.com/ontologies/product-market-codes/B1700XAllergologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H11009Cèl·lules BthubImmunologiathubBiologia molecularthubLlibres electrònicsthubImmunology.Molecular biology.Allergy.Immunology.Molecular Medicine.Allergology.Cèl·lules BImmunologiaBiologia molecular616.0798Wang Ji-Yangedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910409697303321B Cells in Immunity and Tolerance2532343UNINA