01617nls 2200289-a 450 99636554820331620201125090049.01527-379219991102a20159999 s-- aengUSafadrnc<<The>> journal of urology2015-PhiladelphiaPublished for the American Urological Association by Lippincott, Williams & Willkins2015-MensileLa rivista offre una solida copertura dei contenuti clinicamente rilevanti necessari per rimanere in prima linea nel campo dinamico dell'urologia .Questa prestigiosa rivista presenta studi investigativi su aree critiche di ricerca e pratica, articoli di indagine che forniscono brevi condensazioni della migliore e più importante letteratura di urologia a livello mondiale e rapporti orientati alla pratica su osservazioni cliniche significative. Il Journal of Urology copre l'ampio ambito di urologia, includendo l'urologia pediatrica, l'oncologia urologica (cancro), il trapianto renale, l'infertilità maschile, i calcoli (calcoli del tratto urinario), l'urologia femminile (incontinenza urinaria e disturbi del rilassamento dello sbocco pelvico), la neurourologia (disturbi minzionali, valutazione urodinamica dei pazienti e disfunzione erettile o impotenza).UrologiaPeriodiciBNCF616.6005American Urological Association.ITcbaREICAT996365548203316EJERJournal of urology791406UNISA03891nam 22005415 450 991040968280332120250610110623.03-030-45493-210.1007/978-3-030-45493-7(CKB)5310000000016732(MiAaPQ)EBC6236226(DE-He213)978-3-030-45493-7(PPN)248596187(MiAaPQ)EBC6236134(MiAaPQ)EBC29090987(EXLCZ)99531000000001673220200623d2020 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierNeurodevelopmental Disorders Employing iPSC Technologies to Define and Treat Childhood Brain Diseases /edited by Emanuel DiCicco-Bloom, James H. Millonig1st ed. 2020.Cham :Springer International Publishing :Imprint: Springer,2020.1 online resource (307 pages)Advances in Neurobiology,2190-5215 ;253-030-45492-4 1. Modeling neurodevelopmental deficits in Tuberous Sclerosis Complex with stem cell-derived neural precursors and neurons -- 2. Advances in human stem cells and genome editing to understand and develop treatment for Fragile X syndrome -- 3. IPSC MODELS OF CHROMOSOME 15Q IMPRINTING DISORDERS: FROM DISEASE MODELING TO THERAPEUTIC STRATEGIES -- 4. Creating iPSC based models to understand the signaling and cellular phenotypes in idiopathic autism and 16p11.2 derived neurons -- 5. Dysregulation of Neurite Outgrowth and Cell Migration in Autism and other Neurodevelopmental Disorders -- 6. Investigation of Schizophrenia with Human Induced Pluripotent Stem Cells -- 7. Modeling Inflammation on Neurodevelopmental disorders using pluripotent stem cells -- 8. Astrocyte-derived exosomes in an iPSC model of bipolar disorder -- 9. Two- and there-dimensional stem cell models to define mechanisms underlying psychiatric disorders -- 10. Development of a 3-D organoid system using human induced pluripotent stem cells to model idiopathic autism.This book contains a compendium of induced pluripotent stem cells (iPSCs) articles and reviews concerning state of the art technologies and how they are being applied to human neurodevelopmental disorders. With the establishment of effective technologies to produce iPSCs and their derivatives, like neural precursors, neurons, and glia, researchers have new platforms to study neurodevelopmental disorders. iPSC technology enables researchers to study how human neurons develop in individuals with neurodevelopmental disorders, providing an unparalleled opportunity to investigate their etiology. In turn, researchers have now begun to understand the underlying molecular and cellular pathways that contribute to human diseases. iPSCs technologies also provide an emerging tool for future translational studies and disease classification. The chapters will emphasize how among the diverse idiopathic and genetic disorders, there are common clinical as well as cellular and molecular phenotypes.Advances in Neurobiology,2190-5215 ;25NeurosciencesNeuroscienceshttps://scigraph.springernature.com/ontologies/product-market-codes/B18006Malalties neurodegenerativesthubLlibres electrònicsthubNeurosciences.Neurosciences.Malalties neurodegeneratives618.9DiCicco-Bloom Emanueledthttp://id.loc.gov/vocabulary/relators/edtMillonig James Hedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910409682803321Neurodevelopmental disorders2056464UNINA