04144nam 2200997z- 450 9910404091503321202102113-03928-713-3(CKB)4100000011302223(oapen)https://directory.doabooks.org/handle/20.500.12854/56130(oapen)doab56130(EXLCZ)99410000001130222320202102d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierPharmaceutical CrystalsMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (148 p.)3-03928-712-5 The crystalline state is the most commonly used essential solid active pharmaceutical ingredient (API). The characterization of pharmaceutical crystals encompasses many scientific disciplines, but the core is crystal structure analysis, which reveals the molecular structure of essential pharmaceutical compounds. Crystal structure analysis provides important structural information related to the API's wide range of physicochemical properties, such as solubility, stability, tablet performance, color, and hygroscopicity. This book entitled "Pharmaceutical Crystals"" focuses on the relationship between crystal structure and physicochemical properties. In particular, the new crystal structure of pharmaceutical compounds involving multi-component crystals, such as co-crystals, salts, and hydrates, and polymorph crystals are reported. Such crystal structures were investigated in the latest studies that combined morphology, spectroscopic, theoretical calculation, and thermal analysis with crystallographic study. This book highlights the importance of crystal structure information in many areas of pharmaceutical science and presents current trends in the structure-property study of pharmaceutical crystals. The Guest Editors of this book hope the readers enjoy a wide variety of recent studies on Pharmaceutical Crystals.Chemistrybicssc1H-indole34-b]indol-4-one5-dihydro-4H-pyrimido[5adefovir dipivoxilBenzodioxolecarbamazepinecocrystalcocrystal formationcrystal habitcrystal structureCrystal structurecrystal structure analysisdehydrationDFTDFT studydicarboxylic aciddissolutionfamotidinefamoxadoneHBVhepatitis BHirshfeld surface analysisHOMO-LUMOhydratehydrogen bondhydrogen bondinghydrogen-bond-acceptance abilityhygroscopicityImidazoleliquid assisted grindingmalonic acidmelting diagrammolecular docking studyn/aNitrofurantoin-4-dimethylaminopyridine (NF-DMAP) salton-line monitoringondansetronpharmaceutical cocrystalpharmaceutical crystalsphotostabilityphysicochemical propertiespolymorphspyrimidin-4(3H)-oneRaman spectroscopyreactivity descriptorssaccharinsalt optimizationSemicarbazonesolubilitysolution crystallizationsolvent-mediated polymorphic transformationstructure determination from powder diffraction datasuccinic acidticagrelorChemistryUekusa Hidehiroauth1297602Yonemochi EtsuoauthBOOK9910404091503321Pharmaceutical Crystals3024601UNINA