07301nam 2202065z- 450 9910404091203321202102113-03928-539-4(CKB)4100000011302226(oapen)https://directory.doabooks.org/handle/20.500.12854/51086(oapen)doab51086(EXLCZ)99410000001130222620202102d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierKidney Inflammation, Injury and RegenerationMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (496 p.)3-03928-538-6 Acute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of subsequent chronic kidney disease. Although the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function is urgently needed. The Special Issue covers research articles that investigated the molecular mechanisms of inflammation and injury during different renal pathologies, renal regeneration, diagnostics using new biomarkers, and the effects of different stimuli like medication or bacterial components on isolated renal cells or in vivo models. The Special Issue contains important reviews that consider the current knowledge of cell death and regeneration, inflammation, and the molecular mechanisms of kidney diseases. In addition, the potential of cell-based therapy approaches that use mesenchymal stromal/stem cells or their derivates is summarized. This edition is complemented by reviews that deal with the current data situation on other specific topics like diabetes and diabetic nephropathy or new therapeutic targets.Medicine and Nursingbicssc2-kidney-1-clip2k1cacute and chronic kidney diseaseacute kidney failureacute kidney injuryAKIallograft rejectionalport syndromeapoptosisarachidonic acidB-cell attracting chemokinebiomarkersC-reactive proteincAMP Regulatory Element Binding Protein (CREB)chemerinchronic kidney diseasechronic kidney disease (CKD)chronic kidney injuryClass IIa Histone Deacetylases (HDAC)CmklR1conditioned mediumcPLA2 and COX-2CREB Regulated Transcriptional Coactivators (CRTC)CXCL13cyclooxygenasecytochrome P450cytotoxicitydapagliflozindiabetes mellitusdiabetic kidney diseasediabetic kidney diseasesdiabetic nephropathydiagnosticsdifferentiationDSS-colitisempagliflozinendotoxemiaendotoxemia-induced oliguric kidney injuryepithelial cellsexosomeexosomesextracellular vesiclesFarnesiferol Bfibrosisfocal segmental glomerulosclerosisG-protein-coupled bile acid receptor (TGR5)genotypeglomerular basement membraneglomerular damageglomerular filtration barrier (GFB)glomerular injuryglomerulusGLP-1 receptor agonistshaemhematuriahypertensionIgA nephropathyIL-18inflammationinflammatory bowel disease (IBD)inflammatory makerinjuryinterleukin-6ischemia-reperfusionischemia/reperfusion injurykidneykidney inflammationkidney injurykidney proximal tubulekidney transplantationKIT assayKIT-IgA scorelipoxygenaselncRNAlong non-coding RNAlong non-coding RNAsLPS-binding proteinlysophosphatidic acidlysophosphatidic acid receptormesenchymal stem cellmesenchymal stem cellsmesenchymal stromal cellsmesodermal stem cellmicroRNAmicroRNAsmiRNAmodified-MSCsmodifier genemolecular mechanismsmolecular signalingmyofibroblastn/anatural productsnecrosisnephrinnichesNLRP3 inflammasomenon-coding RNAsnoninvasiveNuclear Factor kappa-light-chain-enhancer of activated B cells (NF-?B)obese kidney fibrosisomega-3 fatty acidoxidative stresspapillapericytepigment nephropathypodocinpodocytepolymorphismpolyploidizationpolyunsaturated fatty acidspredictionproximal tubuleregulated necrosisrenal cell carcinomarenal fibrosisrenal inflammationrenal injuryrenal ischemia-reperfusionrenal progenitorsrenal stem cellsrenal tubular cellsrenovascular hypertensionrhabdomyolysisROSSalt Inducible Kinase (SIK)scattered tubular cellsSGLT2 inhibitorssignal transductionsignaling cascadeslit diaphragmstem cellT cell-mediated rejectionTaiwantherapeutic targettherapeutics targetsThy1.1 nephritistranscriptiontubular injurytype I collagentype IV collagentype V collagenxanthine oxidaseMedicine and NursingKoch Benjaminauth1331944Geiger HelmutauthBaer Patrick CauthBOOK9910404091203321Kidney Inflammation, Injury and Regeneration3040686UNINA