05813nam 2201633z- 450 991040408860332120231214132828.03-03928-311-1(CKB)4100000011302252(oapen)https://directory.doabooks.org/handle/20.500.12854/54592(EXLCZ)99410000001130225220202102d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNew Insights into Parvovirus ResearchMDPI - Multidisciplinary Digital Publishing Institute20201 electronic resource (342 p.)3-03928-310-3 Viruses in the Parvoviridae family constitute one of the most diverse and intriguing fields of research. While they all share an ssDNA genome and a small capsid, they can differ widely in structure, genome organization and expression, virus–cell interaction, and impact on the host. Exploring such diversity and unraveling the inherent complexity in these apparently simple viruses is an ongoing endeavor and commitment for the scientific community. The translational implications of research on parvoviruses are relevant. Within the family, some viruses are important human and veterinary pathogens, in need of diagnostic methods and antiviral strategies; other viruses have long been studied and engineered as tools for oncolytic therapy, or as sophisticated gene delivery vectors, and can now display their wide and expanding applicative potential. This Special Issue of Viruses collects recent contributions in the field of parvovirus research, with a focus on new insights and research on unresolved issues, as well as new approaches exploiting systemic methodologies. Evolution, structural biology, viral replication, virus–host interaction, pathogenesis and immunity, and viral oncotherapy are a selection of the topics addressed in the issue that can be of relevance to the community involved in parvovirus research and of interest to a wider audience.antiviralsBombyx mori bidensovirusBocaparvovirushuman bocavirus 1equine parvovirus-hepatitisNS2NS1X-ray crystallographyBIRC3 (cIAP-2)glycanschildrenantibody interactionsnew virusesalpacacidofovirrodent protoparvovirusesclinical trialsstructural biologyDNA virushuman bocaviruscaspase-3viral communitiesuncoatingPLA2phospholipase-A2oncolytic virus immune therapyParvoviridaeviral ecologyCryo-EMAAVmetagenomicsphylogenyoncolytic virusesmiteparvovirus evolutionCarnivore protoparvovirus 1adeno-associated virustelbivudinecapsid stabilityvirushomology modelinghuman airway epitheliasequence analysisacute gastroenteritisbisulfite PCRnext-generation sequencingsingle stranded DNA virusoverlapping promotersvirus diversityprognosisoncolytic activitygenomehydroxyureaLepidopteragenome externalizationantiviral compoundscirculating angiogenic cellstumor microenvironmentcoumarin derivativesnuclear targetingdensovirusreceptor interactionscell cycle arresttranscription profilebrincidofovircanine parvovirusendogenous viral elementsinflammatory cardiomyopathyerythroid progenitor cellsRNA-seqinsectchapparvovirusRT-qPCRtraffickingAAV2agricultural pestsAdeno-associated virusmyocarditisdiagnosisparvovirusfeline panleukopenia viruschitinB19Vtranscription mappingflavonoidsimmunomodulationerythrovirusapoptosisadenoviral vectoranti-cancerdivalent cationsproteasegeneticspreclinicalarthropodperitrophinsbiocontroldilated cardiomyopathyinsect parvoviruscombination therapiesintravenous immunoglobulin (IVIG)virus phylogenyevolutionsecond generation parvovirus treatmentscommercial horse serumparvovirus B19canine chapparvovirusCpG methylationRACEH-1PVviral metagenomicshorsesGallinella Giorgioauth1311911BOOK9910404088603321New Insights into Parvovirus Research3035501UNINA