03396nam 2201081z- 450 991040407790332120231214132817.03-03928-918-7(CKB)4100000011302359(oapen)https://directory.doabooks.org/handle/20.500.12854/55413(EXLCZ)99410000001130235920202102d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierOrgans-on-chipsMDPI - Multidisciplinary Digital Publishing Institute20201 electronic resource (262 p.)3-03928-917-9 Recent advances in microsystems technology and cell culture techniques have led to the development of organ-on-chip microdevices that produce tissue-level functionality, not possible with conventional culture models, by recapitulating natural tissue architecture and microenvironmental cues within microfluidic devices.tissue engineeringmicrofluidic deviceischemia/reperfusion injurysyringe pumpliver-on-a-chipvacuum chuckepithelial-endothelial interfacevessel branchingorgans-on-chipsnanogroovespassive deliveryfunctional neuron imagingorgan-on-a-chiplung epithelial cellMEMSdrug absorptionstrain3D cell culture systemmechanical cuemulti-cultureangiogenesishigh-throughput screeningfluoroelastomermembranescell cultureparacellular/transcellular transportbeating forcemicrofabricationdrug hepatotoxicitybiomimetic oxidationcompressionmicrofluidicssurfactant proteinPDMSneuronal cell networksneuronal guidancetrans-epithelial electrical resistancespheroid arrayorgan-on-a-chip (OOC)biomechanicscellorgan-on-chipsorgan-on-chipstretchshear stressshear flowimage-based screeningdrug metabolismvascularizationhuman induced pluripotent Stem cell-derived cardiomyocytes (hiPS-CM)stressbarrier permeabilitybio-mechanical propertycardiac 3D tissueendothelial cell activationorganoidsiliconlattice light-sheet microscopyintegrated pumpSH-SY5Y cellsthrombolysis3D cell cultureneuronal cellsdrug efficacyvascularized tumor modelTung Yi-Chungauth1290543Torisawa Yu-sukeauthBOOK9910404077903321Organs-on-chips3021527UNINA