04612nam 2201129z- 450 9910404077703321202102113-03928-789-3(CKB)4100000011302361(oapen)https://directory.doabooks.org/handle/20.500.12854/56085(oapen)doab56085(EXLCZ)99410000001130236120202102d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierPesticidal Plants: From Smallholder Use to CommercialisationMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (184 p.)3-03928-788-5 The global biodiversity and climate emergencies demand transformative changes to human activities. For example, food production relies on synthetic, industrial and non-sustainable products for managing pests, weeds and diseases of crops. Sustainable farming requires approaches to managing these agricultural constraints that are more environmentally benign and work with rather than against nature. Increasing pressure on synthetic products has reinvigorated efforts to identify alternative pest management options, including plant-based solutions that are environmentally benign and can be tailored to different farmers' needs, from commercial to small holder and subsistence farming. Botanical insecticides and pesticidal plants can offer a novel, effective and more sustainable alternative to synthetic products for controlling pests, diseases and weeds. This Special Issue reviews and reports the latest developments in plant-based pesticides from identification of bioactive plant chemicals, mechanisms of activity and validation of their use in horticulture and disease vector control. Other work reports applications in rice weeds, combination biopesticides and how chemistry varies spatially and influences the effectiveness of botanicals in different locations. Three reviews assess wider questions around the potential of plant-based pest management to address the global challenges of new, invasive and established crop pests and as-yet underexploited pesticidal plants.Pesticidal Plantsacaricideagro-ecological intensificationaniseantifeedantaphidsbarnyard grassbiopesticidebiopesticidesbotanical active substancesbotanical insecticidesbotanical pesticidebotanical pesticidesbotanicalschemotype 3Colorado potato beetlecorncover cropsdeguelinencapsulationentomopathogenic fungiessential oilsfennelfoliar fertilisergrowth inhibitorinduced systemic responseinsect behaviorinsect pestinsecticidal activityinsectsintegrated pest managementinvasive speciesItalian ryegrasskaranjaleaf disc assaylimonoidMelia volkensiiMeliaceaeneemoil emulsion entrapmentorganic farmingorganic pesticideparasitoidpest managementpesticidal plantpestsphenylalaninephytotoxic activityprospectspyrethrumpyrrolizidine alkaloidresistancericerotenoidsrutinSenecio fistulosussesquiterpenespatial-temporal variationspray dryingstructure-activity relationshipssurvival analysissustainable agriculturesynergismTetranychus urticaetryptophanweed controlY-tube olfactometerIsman Murray Bauth91917Stevenson Philip CauthBelmain Steven RauthBOOK9910404077703321Pesticidal Plants: From Smallholder Use to Commercialisation3020450UNINA02620nam 2200469z- 450 991022734710332120210211(CKB)4100000000883862(oapen)https://directory.doabooks.org/handle/20.500.12854/42833(oapen)doab42833(EXLCZ)99410000000088386220202102d2017 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierThe CB2 Cannabinoid System: A New Strategy in Neurodegenerative Disorder and NeuroinflammationFrontiers Media SA20171 online resource (100 p.)Frontiers Research Topics2-88945-223-9 The neurodegenerative disorders such as Parkinson's disease (PD) or Alzheimer's disease (AD) are the most common forms of dementia and no pharmacological treatments are to date available for these diseases. Indeed, the only used drugs are symptomatic and no useful to block the progression of the diseases. The lack of a therapeutic approach is also due to a lack of an early diagnosis. This Research Topic describes a new target that is involved in the firs step of these disorders and that can be useful for the treatment and the diagnosis of such pathologies: the cannabinoid receptor subtype 2 or CB2R. Indeed, CB2R is overexpressed in reactive microglia and activated astrocytes during neuroinflammation and thus their detection by PET probes can be an easily strategy for an early diagnosis of neurodegeneration. Moreover, CB2 agonists and inverse agonists displayed neuroprotective effects and they so can be candidated as new therapeutich drugs for the treatment of these pathologies. Therefore, the aim of this Research Topic is to show the great potential of CB2R ligands for the development of new tools/drugs for both the therapy and the diagnosis of neurodegeneration.CB2 Cannabinoid SystemNeurosciencesbicsscADCannabinod systemCB2 receptorCB2R agonistCB2R inverseInflammationneurodegenerationPDNeurosciencesMarialessandra Continoauth1304687Nicola A. ColabufoauthElena CapparelliauthAshley I. BushauthBOOK9910227347103321The CB2 Cannabinoid System: A New Strategy in Neurodegenerative Disorder and Neuroinflammation3027605UNINA