05310nam 22007815 450 991037391320332120220601175049.03-030-24100-910.1007/978-3-030-24100-1(CKB)4100000009845266(DE-He213)978-3-030-24100-1(MiAaPQ)EBC5977068(PPN)257359710(EXLCZ)99410000000984526620191111d2019 u| 0engurnn#008mamaatxtrdacontentcrdamediacrrdacarrierTranslational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics /edited by Erika Ruiz-Garcia, Horacio Astudillo-de la Vega1st ed. 2019.Cham :Springer International Publishing :Imprint: Springer,2019.1 online resource (X, 171 p. 19 illus. in color.)Advances in Experimental Medicine and Biology,0065-2598 ;11683-030-24099-1 Preface -- Pharmaco-Geno-Proteo-Metabolomics and Translational Research in Cancer -- Next generation sequencing (NGS): a revolutionary technology in pharmacogenomics and personalized medicine in Cancer -- Pharmaco-epigenomics: on the road of translation medicine -- Design and Implementing Pharmacogenomics Study in Cancer -- Onco-omics approaches and applications in Clinical Trials for Cancer patients -- Issues and Ethical Considerations in Pharmaco-oncogenomics -- Pharma-oncogenomics in the era of personal genomics: a quick guide to online resources and tools -- Inmuno-Oncology in the era of Personalized Medicine -- CAR T Cell and Personalized Medicine -- Oncobiome at the forefront of a novel molecular mechanism to understand the Microbiome and Cancer -- Nutrition, Cancer and Personalized Medicine -- Index.This book presents concise chapters written by internationally respected experts on various important aspects of translational cancer genomics, offering a comprehensive overview of the onco-omics applications in the new era of cancer personal genomics research field. Being a complex disease that affects millions of people worldwide, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. In the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and even more, considering the immune system, the metabolism and in the near future the microbiome, all areas nowadays related in the prognosis and treatment of cancer patients. These contributions are either critical reviews or clinical and basic research reports. The topics discussed here include evidence-based medicine and provides useful information on translational cancer research to clinicians and biomedical scientists in order to offer another vision of cancer origin beyond the traditional causes or the oncogenic maintenance concept proposed by the oncogene addiction theory.Advances in Experimental Medicine and Biology,0065-2598 ;1168Molecular biologyCancer researchPharmaceutical technologyImmunologyBiomedical engineeringGeneticsMolecular Medicinehttps://scigraph.springernature.com/ontologies/product-market-codes/B1700XCancer Researchhttps://scigraph.springernature.com/ontologies/product-market-codes/B11001Pharmaceutical Sciences/Technologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B21010Immunologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B14000Biomedical Engineering/Biotechnologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B24000Genetics and Genomicshttps://scigraph.springernature.com/ontologies/product-market-codes/L32000Medicina personalitzadathubCàncerthubLlibres electrònicsthubMolecular biology.Cancer research.Pharmaceutical technology.Immunology.Biomedical engineering.Genetics.Molecular Medicine.Cancer Research.Pharmaceutical Sciences/Technology.Immunology.Biomedical Engineering/Biotechnology.Genetics and Genomics.Medicina personalitzadaCàncer611.01816Ruiz-Garcia Erikaedthttp://id.loc.gov/vocabulary/relators/edtAstudillo-de la Vega Horacioedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910373913203321Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics2140617UNINA