04748nam 2201225z- 450 991036775760332120231214133136.03-03921-575-2(CKB)4100000010106141(oapen)https://directory.doabooks.org/handle/20.500.12854/57721(EXLCZ)99410000001010614120202102d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierRecent Advances in Biocatalysis and Metabolic Engineering for BiomanufacturingMDPI - Multidisciplinary Digital Publishing Institute20191 electronic resource (278 p.)3-03921-574-4 The use of biocatalysts, including enzymes and metabolically engineered cells, has attracted a great deal of attention in the chemical and bio-industry, because biocatalytic reactions can be conducted under environmentally-benign conditions and in more sustainable ways. The catalytic efficiency and chemo-, regio-, and stereo-selectivity of enzymes can be enhanced and modulated using protein engineering. Metabolic engineering seeks to enhance cellular biosynthetic productivity of target metabolites via controlling and redesigning metabolic pathways using multi-omics analysis, genome-scale modeling, metabolic flux control, and reconstruction of novel pathways. The aim of this book is to cover the recent advances in biocatalysis and metabolic engineering for biomanufacturing of biofuels, chemicals, biomaterials, and pharmaceuticals. Reviews and original research articles on the development of new strategies to improve the catalytic efficiency of enzymes, biosynthetic capability of cell factories, and their applications in production of various bioproducts and chemicals are included.fluorescein diacetateMethylosinus sporium strain 5soluble methane monooxygenasetunable expression systemFTIR spectroscopymevalonate kinase 1poly(ethylene glycol)tetraethylene glycolreviewmevalonate (MVA)biofilm5-hydroxymethylfurfuralpolymer functionalizationmicrobial productionmicrobial cell factorybio-hydrogenredox enzymesspecific recognitionfed-batch fermentationmonoterpeneVitreoscillaPvgbbioreactor3-hydroxypropionic acidcascade reactionssynthetic biologyaerobic methane bioconversionstarch hydrolysisCYP153AMEP pathwaycross-linked enzyme aggregateinterfacial activationexpression vectorsCombi-CLEAspolyethyleneiminebovine serum albuminpolyurethane foam12-hydroxydodecanoic acidMEV pathwayamyloglucosidasetotal enzymatic activityNylon 12biocatalytic reactionMyceliophthorawhole-cell biotransformationmagnetic nanoparticleslipase immobilizationMethanosarcina mazeibiocatalysisacetatevgbC-H activationartificial self-sufficient P450whole cellbioplasticsCorynebacterium glutamicumchemicals additionenzyme modulationEversaenzyme stabilizationbiocatalystsprokaryotic microbial factorysynthetic metabolic pathwaysmannoseimmobilization(?)-?-bisabololhydrogenaseO2 activationstring film reactorfatty acid synthesis?-aminododecanoic acidtransesterificationmass transfer performancedodecanoic acidmetabolic engineeringglyoxal oxidasesmall moleculesCandida antarctica Lipase BLee Eun Yeolauth1311271BOOK9910367757603321Recent Advances in Biocatalysis and Metabolic Engineering for Biomanufacturing3030078UNINA