06011nam 2201465z- 450 991036775750332120231214133137.03-03921-364-4(CKB)4100000010106142(oapen)https://directory.doabooks.org/handle/20.500.12854/45199(EXLCZ)99410000001010614220202102d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierDinophysis toxins distribution, fate in shellfish and impacts /special issue editors, Beatriz Reguera, Juan BlancoMDPI - Multidisciplinary Digital Publishing Institute20191 electronic resource (376 p.)3-03921-363-6 Several species of Dinophysis produce one or two groups of lipophilic toxins: okadaic acid (OA) and its derivatives; or the dinophysistoxins (DTXs) (also known as diarrhetic shellfish poisons or DSP toxins) and pectenotoxins (PTXs). DSP toxins are potent inhibitors of protein phosphatases, causing gastrointestinal intoxication in consumers of contaminated seafood. Forty years after the identification of Dinophysis as the causative agent of DSP in Japan, contamination of filter feeding shellfish exposed to Dinophysis blooms is recognized as a problem worldwide. DSP events affect public health and cause considerable losses to the shellfish industry. Costly monitoring programs are implemented in regions with relevant shellfish production to prevent these socioeconomic impacts. Harvest closures are enforced whenever toxin levels exceed regulatory limits (RLs). Dinophysis species are kleptoplastidic dinoflagellates; they feed on ciliates (Mesodinium genus) that have previously acquired plastids from cryptophycean (genera Teleaulax, Plagioselmis, and Geminigera) nanoflagellates. The interactions of Dinophysis with different prey regulate their growth and toxin production. When Dinophysis cells are ingested by shellfish, their toxins are partially biotransformed and bioaccumulated, rendering the shellfish unsuitable for human consumption. DSP toxins may also affect shellfish metabolism. This book covers diverse aspects of the abovementioned topics—from the laboratory culture of Dinophysis and the kinetics of uptake, transformation, and depuration of DSP toxins in shellfish to Dinophysis population dynamics, the monitoring and regulation of DSP toxins, and their impact on the shellfish industry in some of the aquaculture regions that are traditionally most affected, namely, northeastern Japan, western Europe, southern Chile, and New Zealand.Dinophysis ToxinsDinoflagellatesWitOMI analysisDST accumulationmusseldinophysistoxinsdepurationhuman healthpectenotoxins (PTXs)cryptophytesMesodiniumdinophysiscompartmentalizationresistanceJapanese scallopsurf clamHAB monitoringtoxinsorganic matterOMI analysisPTXstime-seriesDiarrhetic shellfish toxinspredator-prey preferencesimmunityokadaic acidphysical-biological interactionsdefensedigestionDinophysisharmful algal bloomspectenotoxinEl Niño Southern Oscillationlysatesuspended particulate matter (SPM)D. caudatamixotrophic culturesMytilus galloprovincialisbivalvesdiarrhetic shellfish poisoningbiotransformationMesodinium cf. rubrumRNA-SeqDST esterificationMesodinium rubrumstatistical analysisseasonalitymass culture conditionsD. acuminata-complexArgopecten purpuratusharmful algal bloompipis (Plebidonax deltoides)DTX-2Reloncaví Fjordpectenotoxinsdeep sequencingclimatic anomalyBrazilqPCRhigh throughput sequencingDSPaccumulationLC/MS/MSProtoceratium reticulatumshellfish toxicitytranscriptomic responseNew Zealandbloomstrophic transfermetabolismbacterial communitykineticsmarine biotoxinsdiarrhetic shellfish toxinsbivalve shellfishDiarrhetic Shellfish Toxins (DST)diarrhetic shellfish toxins (DST)ScotlandDinophysis acuminataDSP toxinstoxin accumulationSouthern Annual ModeDiarrheic Shellfish PoisoningDinophysis toxinsOAmarine toxinstoxin vectorswild harvestDinophysis acutaSydney rock oyster (Saccostrea glomerata)Argopecten irradiansdinophysistoxinPort Underwoodaquacultureniche partitioningDinoflagellates.579.8/7Blanco Juan(Biologist),Reguera BeatrizBOOK9910367757503321Dinophysis toxins3402000UNINA