03311nam 22007933a 450 991036775650332120250203235431.09783039211746303921174910.3390/books978-3-03921-174-6(CKB)4100000010106152(oapen)https://directory.doabooks.org/handle/20.500.12854/59280(ScCtBLL)800ce551-c1d7-496b-981c-c258365711b8(OCoLC)1163826438(EXLCZ)99410000001010615220250203i20192019 uu engurmn|---annantxtrdacontentcrdamediacrrdacarrierSex Hormone Receptor Signals in Human MalignanciesHiroshi MiyamotoBasel, Switzerland :MDPI,2019.1 electronic resource (152 p.)9783039211739 3039211730 Sex steroids, including androgens, estrogens, and progestogens, are knownto have widespread physiological actions beyond the reproductive systemvia binding to the sex hormone receptors. Meanwhile, emerging evidence hasindicated that sex hormone receptor signals are involved in the outgrowth ofsome malignancies, such as prostate and breast carcinomas, as well as othersthat have not traditionally been considered as endocrine-related neoplasms. ThisSpecial Issue "Sex Hormone Receptor Signals in Human Malignancies" coversvarious aspects of the potential role of sex hormone receptors and related signalsin prostate cancer, breast cancer, and other neoplastic conditions by depictingpromising findings derived from in vitro and in vivo experiments as well as theanalyses of surgical specimens. The current observations described may thusprovide a unique insight into novel or known functions of sex hormone receptorsand related molecules.FOXA1COBRA1estrogenprogesterone receptor negativemutational profilingheterogeneous nuclear ribonucleoprotein Kestrogen receptor alphasalivary gland tumorscastration-resistant prostate cancerELK1fibroblastsandrogen receptormelanocytesdrug screening and proteomicsPI3K pathwayNELFBtherapeutic targetsimmunohistochemistryandrogen deprivation therapyovarian cancerestrogen receptorepidermal growth factor receptorethinylestradiolmelanomabreast cancerkeratinocytesG-protein coupled estrogen receptorprognosislevonorgestrelultraviolet radiationsex hormone receptorsupper urinary tract urothelial carcinomaCRPCnuclear factor erythroid 2-related factor 2TP53Miyamoto Hiroshi1297599ScCtBLLScCtBLLBOOK9910367756503321Sex Hormone Receptor Signals in Human Malignancies3024598UNINA