03091nam 2200709z- 450 991036775650332120231214133048.03-03921-174-9(CKB)4100000010106152(oapen)https://directory.doabooks.org/handle/20.500.12854/59280(EXLCZ)99410000001010615220202102d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierSex Hormone Receptor Signals in Human MalignanciesMDPI - Multidisciplinary Digital Publishing Institute20191 electronic resource (152 p.)3-03921-173-0 Sex steroids, including androgens, estrogens, and progestogens, are knownto have widespread physiological actions beyond the reproductive systemvia binding to the sex hormone receptors. Meanwhile, emerging evidence hasindicated that sex hormone receptor signals are involved in the outgrowth ofsome malignancies, such as prostate and breast carcinomas, as well as othersthat have not traditionally been considered as endocrine-related neoplasms. ThisSpecial Issue “Sex Hormone Receptor Signals in Human Malignancies” coversvarious aspects of the potential role of sex hormone receptors and related signalsin prostate cancer, breast cancer, and other neoplastic conditions by depictingpromising findings derived from in vitro and in vivo experiments as well as theanalyses of surgical specimens. The current observations described may thusprovide a unique insight into novel or known functions of sex hormone receptorsand related molecules.FOXA1COBRA1estrogenprogesterone receptor negativemutational profilingheterogeneous nuclear ribonucleoprotein Kestrogen receptor alphasalivary gland tumorscastration-resistant prostate cancerELK1fibroblastsandrogen receptormelanocytesdrug screening and proteomicsPI3K pathwayNELFBtherapeutic targetsimmunohistochemistryandrogen deprivation therapyovarian cancerestrogen receptorepidermal growth factor receptorethinylestradiolmelanomabreast cancerkeratinocytesG-protein coupled estrogen receptorprognosislevonorgestrelultraviolet radiationsex hormone receptorsupper urinary tract urothelial carcinomaCRPCnuclear factor erythroid 2-related factor 2TP53Miyamoto Hiroshiauth1297599BOOK9910367756503321Sex Hormone Receptor Signals in Human Malignancies3024598UNINA