04124nam 22012013a 450 991036775460332120250203235435.09783039216154303921615510.3390/books978-3-03921-615-4(CKB)4100000010106171(oapen)https://directory.doabooks.org/handle/20.500.12854/54644(ScCtBLL)2766e7b8-8858-4e87-add9-3aa631700b49(OCoLC)1163845648(EXLCZ)99410000001010617120250203i20192019 uu engurmn|---annantxtrdacontentcrdamediacrrdacarrierNewborn Screening for Sickle Cell Disease and other HaemoglobinopathiesElena Cela, Jacques Elion, Stephan Lobitz, Raffaella ColombattiBasel, Switzerland :MDPI,2019.1 electronic resource (162 p.)9783039216147 3039216147 Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies is a Special Issue of the International Journal of Neonatal Screening. Sickle cell disease is one of the most common inherited blood disorders, with a huge impact on health care systems due to high morbidity and high mortality associated with the undiagnosed disease. Newborn screening helps to make the diagnosis early and to prevent fatal complications and diagnostic odysseys. This book gives an overview of diagnostic standards in newborn screening for sickle cell disease and examples of existing newborn screening programs.glucose-6-phosphate dehydrogenasehydroxyurea/hydroxycarbamidecord bloodscreeninghemoglobin patterncapillary electrophoresissickle cell disease(recommended) screening panelvaso-occlusive crisisGuthrie spotsnewborn screening)foetal haemoglobinharmonisationreviewbirth prevalenceG6PD deficiencypreventionend-organ damagethalassemiaMALDI-TOFIEFacute chest syndromeIndiasickle cell and thalassaemia screening programme'Getting to Outcomes'newborn screeninghemoglobinopathyservice userspublic health engagementautomated HPLCKaduna Stategene therapy for haemoglobinopathies?-globin genemethodsneonatal screening programmalariaPlasmodium vivaxsub-Saharan Africapatient organisationshealth policypathophysiologySickle Cell Diseasemass spectrometrysickle cell disorderneonatal screeningnon-tribalNigeriapoint-of-careHPLClaboratory methodsregistrypatient advocacybone marrow transplantanaemiahemoglobinopathiestribalnewbornburden of diseasepatient representativesdiagnosticspolicy makinghaemolysisCaribbeanhigh performance liquid chromatography (HPLC)sickle cell disease (SCD)implementation scienceCela Elena1788596Elion JacquesLobitz StephanColombatti RaffaellaScCtBLLScCtBLLBOOK9910367754603321Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies4323636UNINA