05263nam 22015493a 450 991036775290332120250203235428.09783039214969303921496910.3390/books978-3-03921-496-9(CKB)4100000010106188(oapen)https://directory.doabooks.org/handle/20.500.12854/53860(ScCtBLL)af45ff10-511b-49a6-a86e-0ada4144ebab(OCoLC)1163825009(EXLCZ)99410000001010618820250203i20192019 uu engurmn|---annantxtrdacontentcrdamediacrrdacarrierMolecular Research of Endometrial PathophysiologyPaola Viganò, Andrea RomanoBasel, Switzerland :MDPI,2019.1 electronic resource (378 p.)9783039214952 3039214950 The endometrium has been the subject of intense research in a variety of clinical settings, because of its importance in the reproductive process and its role in women's health. In the past 15 years, significant efforts have been invested in defining the molecular phenotype of the receptive phase endometrium as well as of various endometrial pathologies. Although this has generated a wealth of information on the molecular landscape of human endometrium, there is a need to complement this information in light of the novel methodologies and innovative technical approaches. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms of endometrium and endometrium-related disorders. The progress made in the molecular actions of steroids, in the metabolism of steroids and intracrinology, in endometrial intracellular pathways, in stem cells biology, as well as in the molecular alterations underlying endometrium-related pathologies has been the focus of the reviews and papers included.]endometrial stromal cellsendometrial celluterine cancerregenerationstem cell markersRANKchronic endometritissmall RNA sequencingHOXA10Vitamin DPPP2R1Amolecular markertranslational researchangiogenesisendometriosisoestradiolmtDNA mutationsantioxidant responseprotein phosphataseSMAPcirculating tumour cells (CTCs)circulating tumour DNA (ctDNA)estrogen dependentendometrial regenerationmesenchymal stem cellsendometrial cancernichegene expressionphosphoinositide 3-kinaselncRNAsmitochondrial biogenesisinflammationpreclinical studiesmiRNAorthoxenografttight junctionproliferationaromatasetestosteroneCRISPR/Cas9endometriumdevelopmental pathwayPP2Aavatarinfertilityprognosisgene editingkinase inhibitorimplantationhaploinsufficiencycontrast-enhanced CT scanpathwaydehydroepiandrosterone (DHEA)CTCFPIK3CBzinc fingerectopic stromaliquid biopsytype II endometrial carcinomaeutopic and ectopic endometriumpreclinical modelsEDN1uterine aspiratecell contactstumour suppressor genepathogenomicsmitochondrial dynamicsadult stem cellsPIK3CAmurine modelsmenstrual cycleimmunomodulationdecidualisationbreakdownbioluminescence imagingprotein kinasemacrophagesadherens junctionexosomesimmunohistochemistryorthotopic xenograft modeldecidualizationp110?deficit of complex Itargeted therapymesenchymal stem cellsulfataseTRP channelspersonalized medicinemitophagymiR-375migrationmicroRNAgap junctioncancerLGR5miR-139-5pViganò Paola343907Romano AndreaScCtBLLScCtBLLBOOK9910367752903321Molecular Research of Endometrial Pathophysiology3022299UNINA