01729nam0 22003733i 450 RMS268872520251003044347.0978885752756720220530d2014 ||||0itac50 baitaitaitz01i xxxe z01nz01ncRDAcarrierFrontiere mobiliimplicazioni etiche della ricerca biotecnologicaa cura di Lorenzo ChieffiMilanoUdineMimesis 2014362 p.21 cmMimesis. Quaderni di bioetica. Nuova serie5001MIL08290252001 Mimesis. Quaderni di bioetica. Nuova serie5Frontiere mobili CFI10326171044108BIOTECNOLOGIAAspetti moraliFIRRAVC059990I174.29Etica delle professioni sanitarie. Soggetti specifici e rami della medicina22174.9ETICA DI ALTRE PROFESSIONI E OCCUPAZIONI21Chieffi, Lorenzo <1955- >CFIV103462340Mimesis <casa editrice>RAVV458808ITIT-00000020220530IT-BN0095 IT-NA0580 NAP PSSALA B $NAP 01POZZO LIB.Vi sono collocati fondi di economia, periodici di ingegneria e scienze, periodici di economia e statistica e altri fondi comprendenti documenti di economia pervenuti in dono. RMS2688725Biblioteca Centralizzata di Ateneo1 v. 01POZZO LIB.ECON MON 4677 01S 0090042215E VMA 1 v. (Precedente collocazione: EC S 4 221)B 2017101120171011 01 PSFrontiere mobili1044108UNISANNIO04352nam 22011053a 450 991036775140332120250203235433.09783039215836303921583310.3390/books978-3-03921-583-6(CKB)4100000010106203(oapen)https://directory.doabooks.org/handle/20.500.12854/53824(ScCtBLL)5fc187e9-5edd-4bb3-99d9-ba19ad58202b(OCoLC)1163845405(oapen)doab53824(oapen)53824(EXLCZ)99410000001010620320250203i20192019 uu engurmn|---annantxtrdacontentcrdamediacrrdacarrierMolecular Basis of Cardiovascular Diseases : Implications of Natriuretic Peptides /Speranza Rubattu, Massimo VolpeMDPI - Multidisciplinary Digital Publishing Institute2019Basel, Switzerland :MDPI,2019.1 electronic resource (212 p.)9783039215829 3039215825 The natriuretic peptides (NPs) family includes a class of hormones and their receptors needed for the physiological control of cardiovascular functions. The discovery of NPs provided a fundamental contribution into our understanding of the physiological regulation of blood pressure, and of heart and kidney functions. NPs have also been implicated in the pathogenesis of several cardiovascular diseases (CVDs), including hypertension, atherosclerosis, heart failure, and stroke. A fine comprehension of the molecular mechanisms dependent from NPs and underlying the promotion of cardiovascular damage has contributed to improve our understanding of the molecular basis of all major CVDs. Finally, the opportunity to target NPs in order to develop new therapeutic tools for a better treatment of CVDs has been developed over the years. The current Special Issue of the Journal covers all major aspects of the molecular implications of NPs in physiology and pathology of the cardiovascular system, including NP-based therapeutic approaches.Medicinebicsscpostmortem biochemistrymedullaanimal modelsremodelingBNPPCSK9guanylyl cyclase/natriuretic peptide receptor-Acardiorenal syndromeforensic medicinepreserved ejection fractionkidneyrenin-angiotensin-aldosterone systematrial fibrillationvasopressorcongestive heart failureatrial natriuretic peptidegene-knockoutobesityheart failureangiogenesisadipose tissuevascularLDL receptormetabolic syndromelinkage analysiscardiometabolic diseasecardiomyocytecardiac dysfunctioncardiac hypertrophyinsulinlipid metabolismcGMPIdiopathic Pulmonary Arterial Hypertension (IPAH)Natriuretic Peptide Clearance Receptor (NPR-C) signalinggene-duplicationrenin–angiotensin systemnatriuretic peptidesangiotensin receptor–neprilysin inhibitorcardiac remodellingARNiNT-proBNPinflammationpulmonary arterial hypertensionvascular homeostasisendothelial cellAtrial Natriuretic peptidenatriuretic peptidevasodilatorstrokegenetic variantsarterial hypertensionfibroblastMANPhypertensionguanylyl cyclase receptor AMedicineRubattu Speranza1324890Volpe MassimoScCtBLLScCtBLLBOOK9910367751403321Molecular Basis of Cardiovascular Diseases4318014UNINA