05276nam 22013573a 450 991036774730332120250203235434.09783039216475303921647310.3390/books978-3-03921-647-5(CKB)4100000010106244(oapen)https://directory.doabooks.org/handle/20.500.12854/50545(ScCtBLL)41cc75c2-d00e-4e31-a894-a21419116c8c(OCoLC)1163832688(oapen)doab50545(EXLCZ)99410000001010624420250203i20192019 uu engurmn|---annantxtrdacontentcrdamediacrrdacarrierThe Interplay of Microbiome and Immune Response in Health and DiseasesAmedeo Amedei, Gwendolyn Barceló-CoblijnMDPI - Multidisciplinary Digital Publishing Institute2019Basel, Switzerland :MDPI,2019.1 electronic resource (206 p.)9783039216468 3039216465 [Increasing evidence suggests that microbiota and especially the gut microbiota (the microbes inhabiting the gut including bacteria, archaea, viruses, and fungi) plays a key role in human physiology and pathology. Recent findings indicate how dysbiosis-an imbalance in the composition and organization of microbial populations-could severely impact the development of different medical conditions (from metabolic to mood disorders), providing new insights into the comprehension of diverse diseases, such as IBD, obesity, asthma, autism, stroke, diabetes, and cancer. Given that microbial cells in the gut outnumber host cells, microbiota influences human physiology both functionally and structurally. Microbial metabolites bridge various-even distant-areas of the organism by way of the immune and hormone system. For instance, it is now clear that the mutual interaction between the gastrointestinal tract and the brain (gut-brain axis), often involves gut microbiota, indicating that the crosstalk between the organism and its microbial residents represents a fundamental aspect of both the establishment and maintenance of healthy conditions. Moreover, it is crucial to recognize that beyond the intestinal tract, microbiota populates other host organs and tissues (e.g., skin and oral mucosa). We have edited this eBook with the aim of publishing manuscripts focusing on the impact of microbiota in the development of different diseases and their associated treatments.]Medicinebicsscgastrointestinal diseasessterile inflammationStaphylococcus spp.etiopathogenesiscolitisEscherichia colibacteriophagesatopic dermatitisintravenous immunoglobulin Gadaptive immunity16S rRNA genevaginal microbiotamodularityinnate immunitygut-liver axisdisease activityimmune systemcytokinescommensalsStaphylococcus aureusdysbiosisfecal transplantationTLR mimicryetanerceptdextran sulfate sodiumCAR T-cell3-dihydroxy-4-methoxyBenzaldehydechemo free treatmentStaphylococcus epidermisrheumatoid arthritismicrobiomeco-occurrence networkimmune epigenetics2autoimmunitysuperoxide dismutaseprecision medicinemetabolismadoptive cell transfer (ACT)gut barrierantibioticscheckpoint inhibitorsprobioticsmicrobiotaCandida albicansEnterococcus faecalischronic liver diseasesTCRanaerobic bacteriaHSV2bacteriocinsmethotrexatemicrobial interactionsT cellsvirusmicelymphoid malignanciesHPVmacrophagesanti-TNF-?inflammationchondroitin sulfate disaccharideimmunotherapygenomicsimmuno-oncologydietaerobic bacteriaimmunological nichemelaninhealthchemokinesgut microbiotacutaneous immunityHIVTILcancerglobal networkMedicineAmedei Amedeo1786978Barceló-Coblijn GwendolynScCtBLLScCtBLLBOOK9910367747303321The Interplay of Microbiome and Immune Response in Health and Diseases4319549UNINA