03796nam 2200901z- 450 991036774150332120231214133547.03-03921-703-8(CKB)4100000010106302(oapen)https://directory.doabooks.org/handle/20.500.12854/54046(EXLCZ)99410000001010630220202102d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierThe Multi-Dimensional Contributions of Prefrontal Circuits to Emotion Regulation during Adulthood and Critical Stages of DevelopmentMDPI - Multidisciplinary Digital Publishing Institute20191 electronic resource (188 p.)3-03921-702-X The prefrontal cortex (PFC) plays a pivotal role in regulating our emotions. The importance of ventromedial regions in emotion regulation, including the ventral sector of the medial PFC, the medial sector of the orbital cortex and subgenual cingulate cortex, have been recognized for a long time. However, it is increasingly apparent that lateral and dorsal regions of the PFC, as well as neighbouring dorsal anterior cingulate cortex, also play a role. Defining the underlying psychological mechanisms by which these functionally distinct regions modulate emotions and the nature and extent of their interactions is a critical step towards better stratification of the symptoms of mood and anxiety disorders. It is also important to extend our understanding of these prefrontal circuits in development. Specifically, it is important to determine whether they exhibit differential sensitivity to perturbations by known risk factors such as stress and inflammation at distinct developmental epochs. This Special Issue brings together the most recent research in humans and other animals that addresses these important issues, and in doing so, highlights the value of the translational approach.norepinephrinemedial prefrontal cortexfear extinctionemotion regulationemotion processingconnectivityanticipatory arousalPavloviantriadic neural systems modelprelimbicdevelopmentpositive and negativeratWilliams Syndromepsychological treatmentglia densityanxietyfMRIarea 25anhedoniaadolescenceadolescentautonomicamygdalaneuron densityneuralprefrontal cortexreliabilityfunctional magnetic resonance imaging (fMRI)networkscAMPcognitive controlextinctioninfralimbicNMDArewardcalciumstress adolescenceBDNFmachine learningnegative affecthierarchical controlemotionoccasion settingserotonin transporterventromedial prefrontal cortexpsychophysiologydepressionagingdopamineageRoberts Angelaauth1323549BOOK9910367741503321The Multi-Dimensional Contributions of Prefrontal Circuits to Emotion Regulation during Adulthood and Critical Stages of Development3035661UNINA