04987nam 2200949z- 450 991036773980332120231214133246.03-03921-825-5(CKB)4100000010106319(oapen)https://directory.doabooks.org/handle/20.500.12854/53381(EXLCZ)99410000001010631920202102d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMicro/Nano Devices for Blood AnalysisMDPI - Multidisciplinary Digital Publishing Institute20191 electronic resource (174 p.)3-03921-824-7 The development of micro- and nanodevices for blood analysis is an interdisciplinary subject that demands the integration of several research fields, such as biotechnology, medicine, chemistry, informatics, optics, electronics, mechanics, and micro/nanotechnologies. Over the last few decades, there has been a notably fast development in the miniaturization of mechanical microdevices, later known as microelectromechanical systems (MEMS), which combine electrical and mechanical components at a microscale level. The integration of microflow and optical components in MEMS microdevices, as well as the development of micropumps and microvalves, have promoted the interest of several research fields dealing with fluid flow and transport phenomena happening in microscale devices. Microfluidic systems have many advantages over their macroscale counterparts, offering the ability to work with small sample volumes, providing good manipulation and control of samples, decreasing reaction times, and allowing parallel operations in one single step. As a consequence, microdevices offer great potential for the development of portable and point-of-care diagnostic devices, particularly for blood analysis. Moreover, the recent progress in nanotechnology has contributed to its increasing popularity, and has expanded the areas of application of microfluidic devices, including in the manipulation and analysis of flows on the scale of DNA, proteins, and nanoparticles (nanoflows). In this Special Issue, we invited contributions (original research papers, review articles, and brief communications) that focus on the latest advances and challenges in micro- and nanodevices for diagnostics and blood analysis, micro- and nanofluidics, technologies for flow visualization, MEMS, biochips, and lab-on-a-chip devices and their application to research and industry. We hope to provide an opportunity to the engineering and biomedical community to exchange knowledge and information and to bring together researchers who are interested in the general field of MEMS and micro/nanofluidics and, especially, in its applications to biomedical areas.red blood cellsmetastatic potentialmicrofluidic devicesmicrostructurelens-lessregression analysispower-law fluidnarrow rectangular microchannelbiomedical coatingsXTC-YF cellsred blood cell (RBC) aggregationY-27632finite element methodPOCTCEA detectionimmersed boundary methodsuspensionparticle tracking velocimetrybiomicrofluidicscomputational fluid dynamicsred blood cells (RBCs)modified conventional erythrocyte sedimentation rate (ESR) methodcomputational biomechanicsRBC aggregation indexmicrofabricationmicrofluidicsmorphological analysischronic renal diseasemultiple microfluidic channelscentrifugal microfluidic devicedeformabilitymaster molder using xurography techniquefluorescent chemiluminescencehydrophobic dishpressure-driven flowcell deformabilitymechanophenotypingseparation and sorting techniquesdensity mediumcell adhesionpolymersrheologycircular microchannelblood on chipsmultinucleated cellsvelocitycell analysismicrofluidic chiptwin-image removalcancerLattice-Boltzmann methoddiabeteshyperbolic microchannelMinas Graçaauth1322341Catarino SusanaauthLima Rui AauthBOOK9910367739803321Micro3034887UNINA