03660nam 22005535 450 991037394540332120230209161306.03-030-35213-710.1007/978-3-030-35213-4(CKB)4100000010119004(DE-He213)978-3-030-35213-4(MiAaPQ)EBC6028040(PPN)242848621(EXLCZ)99410000001011900420200124d2020 u| 0engurnn#008mamaatxtrdacontentcrdamediacrrdacarrierBeyond Our Genes Pathophysiology of Gene and Environment Interaction and Epigenetic Inheritance /edited by Raffaele Teperino1st ed. 2020.Cham :Springer International Publishing :Imprint: Springer,2020.1 online resource (VIII, 266 p. 11 illus., 10 illus. in color.)3-030-35212-9 Includes bibliographical references and index.Section I: The physiology of the gene/environment interaction -- Nutrition -- Physical Exercise -- Circadian Rhythm -- Toxicants: Smoke, Alcohol and Heavy Metals -- Hormones -- Section II: Gene-Environment Interaction and Disease Susceptibility -- Obesity and Metabolic Syndromes -- Cancer -- Neurological and Psychiatric Disorders -- Asthma and allergic disorders -- Lamarck Versus Darwin: The Concept of Acquired Epigenetic Inheritance -- Section III: Genome/Epigenome -- Genetic Contribution to Epigenetic Inheritance -- The Controversial Role of DNA Methylation in Epigenetic Inheritance -- Small Non-Coding RNAs -- Chromatin Modifiers -- Soma-to-Germline Information Transfer: Questions and Promises.The genotype/phenotype dichotomy is being slowly replaced by a more complex relationship whereby the majority of phenotypes arise from interactions between one’s genotype and the environment in which one lives. Interestingly, it seems that not only our lives, but also our ancestors’ lives, determine how we look. This newly recognized form of inheritance is known as (epi)genetic, as it involves an additional layer of information on top of the one encoded by the genes. Its discovery has constituted one of the biggest paradigm shifts in biology in recent years. Understanding epigenetic factors may help explain the pathogenesis of several complex human diseases (such as diabetes, obesity and cancer) and provide alternative paths for disease prevention, management and therapy. This book introduces the reader to the importance of the environment for our own health and the health of our descendants, sheds light on the current knowledge on epigenetic inheritance and opens a window to future developments in the field.Human geneticsGeneticsGenetic engineeringHuman Geneticshttps://scigraph.springernature.com/ontologies/product-market-codes/B12008Genetics and Genomicshttps://scigraph.springernature.com/ontologies/product-market-codes/L32000Genetic Engineeringhttps://scigraph.springernature.com/ontologies/product-market-codes/C12037Human genetics.Genetics.Genetic engineering.Human Genetics.Genetics and Genomics.Genetic Engineering.573.21Teperino Raffaeleedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910373945403321Beyond Our Genes2287911UNINA03996nam 22007575 450 991036660280332120230816131701.03-030-24440-710.1007/978-3-030-24440-8(CKB)4100000009678238(MiAaPQ)EBC5969438(DE-He213)978-3-030-24440-8(PPN)272264369(EXLCZ)99410000000967823820191030d2020 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierAerospace Alloys /by Stefano Gialanella, Alessio Malandruccolo1st ed. 2020.Cham :Springer International Publishing :Imprint: Springer,2020.1 online resource (xix, 570 pages) illustrationsTopics in Mining, Metallurgy and Materials Engineering,2364-33073-030-24439-3 Preface -- 1 Introduction to aerospace applications -- 2 Metal based materials for airframe applications -- 3 Materials for gas turbine aero engines -- 4 Steels -- 5 Titanium and titanium alloys -- 6 Superalloys -- 7 Coatings for gas turbine engine -- 8 Hot corrosion -- 9 Other interesting materials for aerospace and related applications.This book presents an up-to-date overview on the main classes of metallic materials currently used in aeronautical structures and propulsion engines and discusses other materials of potential interest for structural aerospace applications. The coverage encompasses light alloys such as aluminum-, magnesium-, and titanium-based alloys, including titanium aluminides; steels; superalloys; oxide dispersion strengthened alloys; refractory alloys; and related systems such as laminate composites. In each chapter, materials properties and relevant technological aspects, including processing, are presented. Individual chapters focus on coatings for gas turbine engines and hot corrosion of alloys and coatings. Readers will also find consideration of applications in aerospace-related fields. The book takes full account of the impact of energy saving and environmental issues on materials development, reflecting the major shifts that have occurred in the motivations guiding research efforts into the development of new materials systems. Aerospace Alloys will be a valuable reference for graduate students on materials science and engineering courses and will also provide useful information for engineers working in the aerospace, metallurgical, and energy production industries.Topics in Mining, Metallurgy and Materials Engineering,2364-3307Building materialsAerospace engineeringAstronauticsSurfaces (Physics)Automotive engineeringCoatingsTribologyStructural MaterialsAerospace Technology and AstronauticsSurface and Interface and Thin FilmAutomotive EngineeringCoatingsTribologyBuilding materials.Aerospace engineering.Astronautics.Surfaces (Physics)Automotive engineering.Coatings.Tribology.Structural Materials.Aerospace Technology and Astronautics.Surface and Interface and Thin Film.Automotive Engineering.Coatings.Tribology.669.94669Gialanella Stefanoauthttp://id.loc.gov/vocabulary/relators/aut1061991Malandruccolo Alessioauthttp://id.loc.gov/vocabulary/relators/autMiAaPQMiAaPQMiAaPQBOOK9910366602803321Aerospace Alloys2521743UNINA