03442nam 22006255 450 991035035240332120220316195624.0981-13-8177-110.1007/978-981-13-8177-5(CKB)4100000009836973(MiAaPQ)EBC5970619(DE-He213)978-981-13-8177-5(PPN)248600389(EXLCZ)99410000000983697320191031d2019 u| 0engurcnu||||||||rdacontentrdamediardacarrierGenome-Wide Association Studies[electronic resource] /edited by Tatsuhiko Tsunoda, Toshihiro Tanaka, Yusuke Nakamura1st ed. 2019.Singapore :Springer Singapore :Imprint: Springer,2019.1 online resource (216 pages) color illustrations981-13-8176-3 Includes bibliographical references.Genotyping and Statistical Analysis -- Genetics of coronary artery disease -- Genetic and Functional Genetics of Autoimmune Diseases -- Genome-Wide Association Study for Type 2 diabetes -- The association of single nucleotide polymorphisms with cancer risk -- Genetics of Infectious Diseases -- Pharmacogenomics -- The Future of and Beyond GWAS.This book examines the utility of genome-wide association studies (GWAS) in the era of next-generation sequencing and big data, identifies limitations and potential means of overcoming them, and looks to the future of GWAS and what may lay beyond. GWAS are among the most powerful tools for elucidating the genetic aspects of human and disease diversity. In Genome-Wide Association Studies, experts in the field explore in depth the impacts of GWAS on genomic research into a variety of common diseases, including cardiovascular, autoimmune, diabetic, cancer, and infectious diseases. The book will equip readers with a sound understanding both of the types of disease and phenotypes that are suited for GWAS and of the ways in which a road map resulting from GWAS can lead to the realization of personalized/precision medicine: functional analysis, drug seeds, pathway analysis, disease mechanism, risk prediction, and diagnosis.Human geneticsCancer researchImmunologyHuman Geneticshttps://scigraph.springernature.com/ontologies/product-market-codes/B12008Cancer Researchhttps://scigraph.springernature.com/ontologies/product-market-codes/B11001Immunologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B14000Genètica humanathubLlibres electrònicsthubHuman genetics.Cancer research.Immunology.Human Genetics.Cancer Research.Immunology.Genètica humana611.01816599.935Tsunoda Tatsuhikoedthttp://id.loc.gov/vocabulary/relators/edtTanaka Toshihiroedthttp://id.loc.gov/vocabulary/relators/edtNakamura Yusukeedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910350352403321Genome-Wide Association Studies1948506UNINA