03557nam 2200721z- 450 991034688010332120231214132826.03-03921-091-2(CKB)4920000000101719(oapen)https://directory.doabooks.org/handle/20.500.12854/54614(EXLCZ)99492000000010171920202102d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNew research in obsessive-compulsive disorder and major depression /special issue editors, Bruno Aouizerate and Emmanuel HaffenMDPI - Multidisciplinary Digital Publishing Institute20191 electronic resource (102 p.)3-03921-090-4 Major depression and obsessive–compulsive disorder (OCD) are now recognized among the most frequent psychiatric disorders, affecting 16–17% and 2–3% of the general population, respectively. They are commonly characterized by: i) a high level of psychiatric and somatic comorbidities; ii) a recurrence or chronic profile; and iii) a negative impact on daily functions, thereby leading to a profound impairment of quality of life. Despite significant advances in pharmacological and psychological therapies over the last decades, unsuccessful responses to standard treatment strategies are classically observed in approximately 20–30% of cases. Therefore, there is a significant need for improving the pathophysiological knowledge through a better identification of environmental, clinical, psychological, genetic, anatomical, and biological determinants, specifically implied in the development, the phenotypic expression, and the relapsing course and/or contributing to the therapeutic failure in major depression and OCD. We are convinced that this research approach is particularly relevant providing critical support for the promotion of innovative treatment alternatives potentially useful for the management of resistant forms of major depression and OCD.Obsessive-compulsive disorderDepression, Mentali-healtholfactionpsychiatryobsessionobsessive-compulsive disordertranscranial direct current stimulationecological momentary assessmentStreptococcus pyogenescytokinesimmunologycompulsioncognitionnosographypediatric autoimmune neuropsychological disorders associated with streptococcal infection (PANDAS)symptoms networksbrain stimulationneuromodulationOCDm-healthcategorizationsecological momentary interventionfictional case studypediatric acute-onset neuropsychiatric syndrome (PANS)Toxoplasma gondiitDCStherapeutic tooldepressionmarkersquality of lifeTourette syndromeObsessive-compulsive disorder.Depression, Mental.616.85/227Aouizerate BrunoHaffen EmmanuelBOOK9910346880103321New Research in Obsessive-Compulsive Disorder and Major Depression3031930UNINA