02476nam 2200397z- 450 9910346720503321202102111000028834(CKB)4920000000094496(oapen)https://directory.doabooks.org/handle/20.500.12854/45668(oapen)doab45668(EXLCZ)99492000000009449620202102d2012 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierECG Based Analysis of the Ventricular Repolarisation in the Human HeartKIT Scientific Publishing20121 online resource (XX, 224 p. p.)Karlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering3-86644-882-1 ECG recordings provide diagnostic relevant information on the de- and repolarisation sequences of the heart. A modification of the repolarisation sequence is assumed to cause Torsades de Pointes. Especially drug induced effects on the repolarisation processes are in focus, since some non-cardiac drugs have been associated with sudden cardiac death in the 1990s. The analysis of the ventricular repolarisation using a set of parameters depicting the morphology of the T-wave is introduced in this work. Therefore, new methods of fully automatic patient-specific QRS detection, beat classification and precise T-wave delineation are presented. Using these methods, medical studies are investigated regarding the modification of the T-wave by different compounds. Also the impact of the heart rate on the morphology of the T-wave is part of this research.The reliable identification of ventricular ectopic beats allows an analysis of the influence of these beats on subsequent heart beats. It turned out that the morphology of subsequent heart beats can significantly be changed. This might give new information on the proarrythmical risk of ventricular ectopic beats.Technology: general issuesbicsscHRTQT intervalQT prolongationRepolarisationT waveTechnology: general issuesBaas Tobiasauth1303447BOOK9910346720503321ECG Based Analysis of the Ventricular Repolarisation in the Human Heart3027056UNINA