05479nam 22015733a 450 991034668900332120250203235425.09783039212668303921266410.3390/books978-3-03921-266-8(CKB)4920000000094779(oapen)https://directory.doabooks.org/handle/20.500.12854/61178(ScCtBLL)f9bc2e79-fe89-403a-a861-bb7a28f563d7(OCoLC)1163839826(oapen)doab61178(EXLCZ)99492000000009477920250203i20192019 uu engurmn|---annantxtrdacontentcrdamediacrrdacarrierTranscriptional Regulation : Molecules, involved Mechanisms and Misregulation /Amelia Casamassimi, Alfredo CiccodicolaMDPI - Multidisciplinary Digital Publishing Institute2019Basel, Switzerland :MDPI,2019.1 electronic resource (356 p.)9783039212651 3039212656 Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. This highly complex and dynamic process is orchestrated by a huge number of molecules and protein networks and occurs through multiple temporal and functional steps. Of note, many human disorders are characterized by misregulation of global transcription since most of the signaling pathways ultimately target components of transcription machinery. This book includes a selection of papers that illustrate recent advances in our understanding of transcriptional regulation and focuses on many important topics, from cis-regulatory elements to transcription factors, chromatin regulators and non-coding RNAs, other than several transcriptome studies and computational analyses.Biology, life sciencesbicssctranscription factortranscriptionself-incompatibilitycytogeneticsepigeneticsselenocysteineteaAP-2?nonsense-mediated decaytranscriptomicsAkt1promotercell metabolismpediveliger larvaePatau Syndrometristetraprolin (TTP)long non-coding RNA (lncRNA)pregnancyG-quadruplexglioblastomaplacentaPRDM gene familycircRNA-disease associationsbioadhesivegene expressionCrassostrea gigastranscription regulationcell differentiationRNA interferencetranscriptomeinflammatory responseFOXO1Adiponectinliquid chromatograph-tandem mass spectrometer (LC-MS/MS)seleniumselenocysteine insertion sequenceinflammationselenoproteinsresearch methodsnutritional statusstructures and functionsCRISPR/Cas9fertilizationmelanindifferentially expressed genestyrosinaseposttranscriptional regulationmajor depressive disorderhuman malignanciespathwayCDKN1Ctranscription factorsp57Kip2enhancer activitymousedisordershigh-throughput RNA sequencing (RNA-Seq)TCGA data analysisRNA-seqheterogeneous networkinsectand drug designtherapeutic targetsmechanismsobesityPacific oysterRsh reguloncommon pathwayPax3somatic mutationsnutritionmolecular dockingbioinformaticsinteractomelong non-coding RNAstranscriptional regulationPteria penguin (RödingAdiponectin receptorstranscriptome profiling1798)N-acyl-l-homoserine lactoneppGpptumorigenesissphingomonadshumandiseaseadenosine and uridine-rich elements (AREs)progress and prospectsmiR-25-3pacute leukemiaNovosphingobium pentaromativorans US6-1microscopycancermolecular pathwayscausal inferenceBiology, life sciencesCasamassimi Amelia1376646Ciccodicola AlfredoScCtBLLScCtBLLBOOK9910346689003321Transcriptional Regulation4317840UNINA