07599nam 2202317z- 450 991034668810332120210211(CKB)4920000000094788(oapen)https://directory.doabooks.org/handle/20.500.12854/56345(oapen)doab56345(EXLCZ)99492000000009478820202102d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierPlant Natural Products for Human HealthMDPI - Multidisciplinary Digital Publishing Institute20191 online resource (514 p.)3-03897-712-8 Plants have served mankind as an important source of foods and medicines. While we all consume plants and their products for nutritional support, a majority of the world population also rely on botanical remedies to meet their health needs, either as their own "traditional medicine" or as "complementary and alternative medicine". From a pharmaceutical point of view, many compounds obtained from plant sources have long been known to possess bio/pharmacological activities, and historically, plants have yielded many important drugs for human use, from morphine discovered in the early nineteenth century to the more recent paclitaxel and artemisinin. Today, we are witnessing a global resurgence in interest and use of plant-based therapies and botanical products, and natural products remain an important and viable source of lead compounds in many drug discovery programs.This Special Issue on "Plant Natural Products for Human Health" compiles a series of scientific reports to demonstrate the medicinal potentials of plant natural products. It covers a range of disease targets, such as diabetes, inflammation, cancer, neurological disease, cardiovascular disease, liver damage, bacterial, and fungus infection and malarial. These papers provide important insights into the current state of research on drug discovery and new techniques. It is hoped that this Special Issue will serve as a timely reference for researchers and scholars who are interested in the discovery of potentially useful molecules from plant sources for health-related applications.MedicinebicsscA?A549 cellsacetaminophenacute liver injuryADadjuvantadjuvant-induced arthritisAmadori rearrangement compoundsAMPKanimalsanti-inflammationanti-malaria activityantifungal activityantioxidant enzymesantiproliferationantistaphylococcal activityantitubercular activityAPAPapoptosisarthritisaspirinAstragali Radixastragaloside IVautomationbergamotbergaptenbiofilmbioinformaticsbiological activitybitter orangebleeding timeBMP/Smadcalorie restrictioncannabigerolcannabinoid type 1 receptorCannabis sativacaspasescatechincelastrolcinnamamidescomputational softwarescopaibacurcumincytoxicitydendritic cellsdietary supplementsdifferentiationdihydromyricetinditerpenoidsdrug design and developmentdrug discoveryEGCGendoplasmic reticulum stressessential oilethnopharmacologyflavonoidflavonoidsfucoidangarlicgenisteinginsengglobal healthglucansgluconeogenesisGlycyrrhiza uralensisgomisin Ngrapefruitgreen teaheartheat-processheme oxygenaseHepaRG cellshepatic steatosishepatotoxicityherb-drug interactionshinokitiolhpatoprotectionhuman healthhuman-hair-follicle dermal papilla cellshyperglycemiaimmune modulationimmunomodulatorinflammationinflammatory bowel diseaseinnovationinsulin resistanceiridoidsischemiaKeap1kumquatlemonlimelipogenesisliposomeslychee seedmandarinmedicinal plantsmelanoma cellmicrobiomemigrationmitochondrial bioenergeticsmitogen-activated protein kinaseMMPsmolecular targetsmorin hydratemouse-hair growthMTT assaymyocardial hypertrophyNAFLDnanoparticlesnatural productsnerolineuroinflammationNeuroprotectiveNrf2nuclear factor-kappaBOH· free radicaloleoresinomicsonionorange petitgrainoxidative stressoxygen consumption rateP. eryngiip53/BaxPanax notoginseng saponinsparacetamolPC12 cellsPenthorum chinense PurshPET inhibitionpharmacokinetic studyPhGsphytocannabinoidphytochemicalsplant natural productplantsPlasmodium parasitesplatelet activationprecision medicinepreclinical studiesprenylated flavonoidsprocyanidin A2protein kinasereperfusionresveratrolrheumatoid arthritisscoulerinesesquiterpenoidsShh/GliSIRT1sirtuin 3small moleculesstructure-activity relationshipsweet orangetargeted deliveryTGF-?thromboembolismtime-kill assaytoxicitytraditional medicineTripterygium wilfordiitriptolidetriterpenic acidsWNT/?-cateninyuzuZiziphus jujubaMedicineZhang Hongjieauth1331913Che Chun-TaoauthBOOK9910346688103321Plant Natural Products for Human Health3040643UNINA