02775nam 22006013a 450 991034667910332120250203235428.09783038975380303897538910.3390/books978-3-03897-538-0(CKB)4920000000094876(oapen)https://directory.doabooks.org/handle/20.500.12854/42586(ScCtBLL)c0be36fe-1f93-49df-8385-a42a9c339e00(OCoLC)1163856964(EXLCZ)99492000000009487620250203i20192019 uu engurmn|---annantxtrdacontentcrdamediacrrdacarrierCalcium Signaling in Human Health and DiseasesFrancesco MocciaBasel, Switzerland :MDPI,2019.1 electronic resource (462 p.)9783038975373 3038975370 Intracellular Ca2+ signaling is witnessing an amazing resurgence of interest. In addition to traditional Ca2+ aficionados, an astonishing (and growing) number of colleagues from all around the world have started to devote a large part of their research to gain insights into the role of Ca2+ signaling in health and disease. This is why calcium ions interact with virtually every signal transduction pathway not only in mammalian cells, but also across the phylogenetic tree, thereby, driving or modulating most, if not all, cellular functions, ranging from fertilization to apoptosis, passing through learning and memory, cardiac contractility, and immune response. This book gathers a collection of original research articles and reviews by a number of renowned experts who aim to present the state of the art of many pathophysiological aspects of intracellular Ca2+ signaling, such as embryonic development, immune response, extracellular Ca2+ signaling, neoplastic transformation, muscle hypertrophy, pulmonary inflammation, and P2X receptor gating.STIMintracellular Ca2+ oscillationsCa2+ signaling5-trisphosphate receptorsneurovascular couplingcardiac contractilityinositol-1SERCANMDA receptorscalcineurinOraiP2X receptorsCa2+-Sensing Receptor4immune responsecancerCa2+-activated K+ channelsmuscle hypertrophyryanodine receptorsMoccia Francesco1786976ScCtBLLScCtBLLBOOK9910346679103321Calcium Signaling in Human Health and Diseases4319547UNINA