04151nam 2201153z- 450 9910404089003321202102113-03921-839-5(CKB)4100000011302248(oapen)https://directory.doabooks.org/handle/20.500.12854/44470(oapen)doab44470(EXLCZ)99410000001130224820202102d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierCyanobacteria and Cyanotoxins: New Advances and Future ChallengesMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (246 p.)3-03921-838-7 Cyanobacteria are a group of ubiquitous photosynthetic prokaryotes. Their occurrence has been increasing worldwide, due to anthropogenic activities and climate change. Several cyanobacterial species are able to synthesize a high number of bioactive molecules, among them, cyanotoxins (microcystins, cylindrospermopsin, nodularin, etc.), which are considered a health concern. For risk assessment of cyanotoxins, more scientific knowledge is required to perform adequate hazard characterization, exposure evaluation and, finally, risk characterization of these toxins. This Special Issue "Cyanobacteria and Cyanotoxins: New Advances and Future Challenges" presents new research or review articles related to different aspects of cyanobacteria and cyanotoxins, and contributes to providing new toxicological data and methods for a more realistic risk assessment.Cyanobacteria and CyanotoxinsMedicinebicssc[d-Leu1]Microcystin-LR16S rRNA gene16S rRNA gene sequencingakinetesanatoxin-aAphanizomenon flos-aquaeapoptosisarcticArtemia salinaastaxanthinbacterial communitybenthic matsbioassaysblue-green algae supplementscyanobacteriacyanobacterial thresholdscyanotoxinscylindrospermopsinCylindrospermopsincytotoxicitydetectiondrinking waterdrinking water treatment plantELISAenergy budgetexposuregenotoxicityharmful algal bloomshemolytic essayHistopathological evaluationin vitrolettuceLithobates catesbeianusmarine cyanobacteriamarine natural compoundsmarine spongesmethod validationmicrobial metabolismsmicrocystinmicrocystin-LRMicrocystin-LRmicrocystin-LR (MC-LR)microcystinsmixturemonoclonal antibodymutagenicityNostocalesnutrient enrichmentoxidative stressParacentrotus lividusPCRphylogenetic analysesProcambarus clarkiiPSP toxinsreproductive toxicityreservoirresveratrolsaxitoxinsecondary metabolitesshotgun metagenomic sequencingsirtuin 1 (SIRT1)tadpolestaste-and-odor compoundstime-resolved fluoroimmunoassayUPLC-MS/MSwater sourceYangtze estuaryMedicineCameán Fernández Ana Maríaauth1824788Jos AngelesauthBOOK9910404089003321Cyanobacteria and Cyanotoxins: New Advances and Future Challenges4392119UNINA02946nam 22006493a 450 991034667910332120250203235428.09783038975380303897538910.3390/books978-3-03897-538-0(CKB)4920000000094876(oapen)https://directory.doabooks.org/handle/20.500.12854/42586(ScCtBLL)c0be36fe-1f93-49df-8385-a42a9c339e00(OCoLC)1163856964(oapen)doab42586(EXLCZ)99492000000009487620250203i20192019 uu engurmn|---annantxtrdacontentcrdamediacrrdacarrierCalcium Signaling in Human Health and DiseasesFrancesco MocciaMDPI - Multidisciplinary Digital Publishing Institute2019Basel, Switzerland :MDPI,2019.1 electronic resource (462 p.)9783038975373 3038975370 Intracellular Ca2+ signaling is witnessing an amazing resurgence of interest. In addition to traditional Ca2+ aficionados, an astonishing (and growing) number of colleagues from all around the world have started to devote a large part of their research to gain insights into the role of Ca2+ signaling in health and disease. This is why calcium ions interact with virtually every signal transduction pathway not only in mammalian cells, but also across the phylogenetic tree, thereby, driving or modulating most, if not all, cellular functions, ranging from fertilization to apoptosis, passing through learning and memory, cardiac contractility, and immune response. This book gathers a collection of original research articles and reviews by a number of renowned experts who aim to present the state of the art of many pathophysiological aspects of intracellular Ca2+ signaling, such as embryonic development, immune response, extracellular Ca2+ signaling, neoplastic transformation, muscle hypertrophy, pulmonary inflammation, and P2X receptor gating.PhysiologybicsscSTIMintracellular Ca2+ oscillationsCa2+ signaling5-trisphosphate receptorsneurovascular couplingcardiac contractilityinositol-1SERCANMDA receptorscalcineurinOraiP2X receptorsCa2+-Sensing Receptor4immune responsecancerCa2+-activated K+ channelsmuscle hypertrophyryanodine receptorsPhysiologyMoccia Francesco1786976ScCtBLLScCtBLLBOOK9910346679103321Calcium Signaling in Human Health and Diseases4319547UNINA