02013nam 2200385z- 450 991034596530332120210212(CKB)4920000000094061(oapen)https://directory.doabooks.org/handle/20.500.12854/61436(oapen)doab61436(EXLCZ)99492000000009406120202102d2018 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierType I Chaperonins: Mechanism and BeyondFrontiers Media SA20181 online resource (104 p.)Frontiers Research Topics2-88945-575-0 Type I chaperonins are key players in maintaining the proteome of bacteria and organelles of bacterial origin. They are well known for their crucial role in mediating protein folding. For almost three decades, the molecular mechanism of chaperonin function has been the subject of intensive research. Still, surprising new mechanistic discoveries are constantly reported. It seems that we are far from having a full understanding of the chaperonin mode of action. Chaperonins are not simply protein folding machines. They also perform diverse extramitochondrial tasks, mainly related to inflammatory and signal transduction processes. This eBook constitutes ten articles highlighting the latest developments related to the divers functions of Type I chaperonins. As its title, mechanism and beyond, the collection starts with mechanistic view, continues with extracellular functions and ends with biotechnological applications of Type I chaperonins.Type I ChaperoninschaperoninGroELGroESHsp10Hsp60Adina Breimanauth1303434Abdussalam AzemauthBOOK9910345965303321Type I Chaperonins: Mechanism and Beyond3027038UNINA