02067nam 2200469z- 450 991034596200332120210211(CKB)4920000000094094(oapen)https://directory.doabooks.org/handle/20.500.12854/42011(oapen)doab42011(EXLCZ)99492000000009409420202102d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierBeyond Borders: Myotonic Dystrophies - A European PerceptionFrontiers Media SA20191 online resource (148 p.)Frontiers Research Topics2-88945-709-5 Myotonic dystrophies (DMs) are pleotropic multisystemic diseases. These dominantly transmitted repeat disorders affect multiple organs of the human body at all ages - from the newborns to the elderly. The present Research Topic represents a timely addition to the expanding body of evidence which aims to provide novel perspectives in our understanding of myotonic dystrophies. This collection of original contributions and standpoint reviews from multiple leading DM centres in Europe describes the state of the art for the characterization of the DMs diseases, the development of molecular strategies to target its multisystemic nature, and provides evidence of screening and testing novel therapeutic avenues.Beyond BordersMedicinebicsscanimal modelsbrain imagingcell modelsCNS involvementDM1DM2multisystemic diseasesmyotonic dystrophy type 1 and type 2phenotypesrepeat disordersMedicineSchoser Benediktauth1767366Meola GiovanniBOOK9910345962003321Beyond Borders: Myotonic Dystrophies - A European Perception4212515UNINA