03420nam 22005775 450 991033751410332120200701233404.03-319-98605-810.1007/978-3-319-98605-0(CKB)4100000007656770(DE-He213)978-3-319-98605-0(MiAaPQ)EBC5923183(PPN)23500636X(EXLCZ)99410000000765677020190213d2019 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierTextbook of Autoinflammation /edited by Philip J. Hashkes, Ronald M. Laxer, Anna Simon1st ed. 2019.Cham :Springer International Publishing :Imprint: Springer,2019.1 online resource (X, 820 p. 154 illus., 135 illus. in color.) 3-319-98604-X Includes bibliographical references and index.Part 1. Basic Science and Biology of Autoinflammation -- Part 2: Autoinflammatory Diseases -- Part 3: Integrative Cross Disease -- Part 4: Pharmacology and Therapies -- Part 5: Measurement and Data Analysis in Autoinflammatory Disease.This book, the first complete textbook on this novel field in Medicine, comprehensively covers the clinical presentation, pathogenesis, genetics, and latest management strategies for autoinflammatory disorders as well as the basic science of autoinflammation. Relevant concepts such as how translational science of genetics and immunology relates to the innate immune system and autoinflammation are covered. Descriptions of the monogenic and polygenic/complex diseases that fall under the umbrella of autoinflammatory diseases are provided. Further topics covered include the latest clinical and genetic diagnostic approaches, concepts on the relationship between autoinflammation and autoimmunity/immunodeficiency, the role of autoinflammation in cancer, treatments and management strategies for these diseases, and potential areas of future development. The Textbook of Autoinflammation systematically describes and reviews diagnostic and treatment options for autoinflammatory disorders as well as all aspects of the concept of autoinflammation, and represents a valuable resource for professionals in a variety of disciplines who encounter these patients or who study autoinflammation.RheumatologyPediatricsImmunologyRheumatologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H33170Pediatricshttps://scigraph.springernature.com/ontologies/product-market-codes/H49006Immunologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B14000Rheumatology.Pediatrics.Immunology.Rheumatology.Pediatrics.Immunology.616.978Hashkes Philip Jedthttp://id.loc.gov/vocabulary/relators/edtLaxer Ronald Medthttp://id.loc.gov/vocabulary/relators/edtSimon Annaedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910337514103321Textbook of Autoinflammation1736781UNINA