05515oam 22004932 450 991032815750332120240110211554.090-04-39119-310.1163/9789004391192(CKB)4920000000028908(nllekb)BRILL9789004391192(oapen)https://directory.doabooks.org/handle/20.500.12854/29504(MiAaPQ)EBC31456969(Au-PeEL)EBL31456969(EXLCZ)99492000000002890820181016d2019 uy 0engurun####uuuuatxtrdacontentnrdamediardacarrierAnimal experimentation working towards a paradigm change /edited by Kathrin Herrmann, Kimberley Jayne1st ed.Brill2019Leiden ;Boston :Brill,2019.1 online resourceHuman-animal studies,1573-4226 ;VOLUME 2290-04-35618-5 Includes bibliographical references and index.Front Matter --Copyright Page --Dedication --Foreword --Preface --Acknowledgements --Contributors --Introduction --Why and How to Shift the Paradigm --Refinement on the Way Towards Replacement: Are We Doing What We Can? /Kathrin Herrmann --How to Evaluate the Science of Non-human Animal Use in Biomedical Research and Testing: A Proposed Format for Debate /Ray Greek and Lisa A. Kramer --How Can the Final Goal of Completely Replacing Animal Procedures Successfully Be Achieved? /Christiane Baumgartl-Simons and Christiane Hohensee --Disease Prevention with a Plant-based Lifestyle /Sabina V. Vyas --Politics and Legislation of Animal Experimentation --Political Campaigning: Where Scientific and Ethical Arguments Meet Public Policy /Emily McIvor --Rethinking the 3Rs: From Whitewashing to Rights /Charlotte E. Blattner --Contesting Animal Experiments through Ethics and Epistemology: In Defense of a Political Critique of Animal Experimentation /Arianna Ferrari --Openness in Animal Experimentation --The Moral Status of Animal Research Subjects in Industry: A Stakeholder Analysis /Sarah Kenehan --Increasing the Transparency of Animal Experimentation: An Australian Perspective /Monika Merkes and Rob Buttrose --Wasted Money in United States Biomedical and Agricultural Animal Research /Jim Keen --The Ethics and Philosophy of Animal Experimentation --Ethics, Efficacy, and Decision-making in Animal Research /Lawrence A. Hansen and Kori Ann Kosberg --Beyond Plausibility Checks: A Case for Moral Doubt in Review Processes of Animal Experimentation /Mara-Daria Cojocaru and Philipp von Gall --Human Wrongs in Animal Research: A Focus on Moral Injury and Reification /Jane Johnson and Anna Smajdor --Effectiveness of the Animal Model --Critically Evaluating Animal Research /Andrew Knight --Extrapolation of Animal Research Data to Humans: An Analysis of the Evidence /Rebecca Ram --Is Animal-based Biomedical Research Being Used in Its Original Context? /Constança Carvalho , Daniel Alves , Andrew Knight and Luis Vicente --The Scientific Problems with Using Non-Human Animals to Predict Human Response to Drugs and Disease /Ray Greek and Lisa A. Kramer --Replacing Animal Tests to Improve Safety for Humans /Kathy Archibald , Robert Coleman and Tamara Drake --Genetic Modification of Animals: Scientific and Ethical Issues /Jarrod Bailey --Animal Research for Alzheimer Disease: Failures of Science and Ethics /John J. Pippin , Sarah E. Cavanaugh and Francesca Pistollato --Behavioral Research on Captive Animals: Scientific and Ethical Concerns /Kimberley Jayne and Adam See --Animal-free Education and Training --Modernizing Biomedical Training: Replacing Live Animal Laboratories with Human Simulation /John Pawlowski , David Feinstein , Marie L. Crandall and Shalin Gala --Humane Education: The Tool for Scientific Revolution in Brazil /Vanessa Carli Bones , Rita de Cássia Maria Garcia , Gutemberg Gomes Alves , Rita Leal Paixão , Alexandro Aluísio Rocha , Karynn Capilé and Róber Bachinski --The Paradigm Shift: Advanced Animal-free Approaches --Recent Developments in Alternatives to Animal Testing /Katy Taylor.Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.Human-Animal Studies22.Animal experimentationEthics & moral philosophyAnimal experimentation.179/.4Herrmann Kathrinedt1739560Herrmann KathrinNL-LeKBNL-LeKBBOOK9910328157503321Animal experimentation4163608UNINA