00962nam0 2200265 450 00000821520070809074601.0280271323X960150145220070809d1999----km-y0itay50------bafreFRy-------001yy<<Le >>principe communautaire d'èquivalence et de reconnaissance mutuelle dans la libre prestation de servicesVassilis Hatzopoulosprefazione di Denys SimonAthenes BruxellesSakkoulas Bruylant1999567 p.24 cmUnione europea - Diritto del lavoro341.76321Hatzopoulos,Vassilis318482Simon,DenysITUNIPARTHENOPE2007RICAUNIMARC000008215H0074034959NAVA320070809Principe communautaire d'equivalence et de reconnaissance mutuelle dans la libre prestation de services984379UNIPARTHENOPE03257 am 2200733 n 450 991031302240332120170808987-3667-57-110.4000/books.eunrn.421(CKB)4960000000012720(FrMaCLE)OB-eunrn-421(oapen)https://directory.doabooks.org/handle/20.500.12854/51993(PPN)225781581(EXLCZ)99496000000001272020180313j|||||||| ||| 0spauu||||||m||||txtrdacontentcrdamediacrrdacarrierLotes sin dueño Derecho de propiedad y abandono como problema urbano /Jorge Paolinelli, Tomás Guevara, Guillermo Oglietti, Alejandra NussbaumViedma Editorial UNRN20171 online resource (138 p.) 987-3667-51-2 Las ciudades argentinas y latinoamericanas presentan una importante conflictividad social por el acceso y la tenencia del suelo urbano. Una manifestación de esa problemática son las tomas de tierra y los procesos de autoproducción de barrios por parte no solo de sectores populares, sino también de capas medias de la población. Otro aspecto de este conflicto es la existencia de tierras que, loteadas en un pasado lejano, están en situación de abandono por propietarios ausentes. Y cabe entonces preguntarse: ¿pueden coexistir propiedades abandonadas con demandas insatisfechas de suelo urbano? Y en todo caso, ¿cómo puede intervenir el Estado ante un andamiaje legal que protege la propiedad sin propietario? Los autores de este libro buscan develar el origen de esta situación paradójica y contribuir a la intervención del Estado a favor de la ampliación del acceso al suelo urbano. Asimismo, para no quedarse en el plano meramente analítico, proponen el estudio del caso de la ciudad de San Carlos de Bariloche y una forma de resolución a partir de una herramienta legislativa concreta.Urban StudiesLawacceso al suelo urbanourbanismohabitatexpropiaciónaccès aux terres urbainesexpropriationurbanismeaccess to urban landtown and country planningtown planningexpropriationhabitataccess to urban landtown planningtown and country planningUrban StudiesLawacceso al suelo urbanourbanismohabitatexpropiaciónaccès aux terres urbainesexpropriationurbanismeaccess to urban landtown and country planningtown planningPaolinelli Jorge1307956Guevara Tomás1307952Oglietti Guillermo1317988Nussbaum Alejandra1307955Colino Evelyn1307951FR-FrMaCLEBOOK9910313022403321Lotes sin dueño3033139UNINA04199nam 22006375 450 991035035030332120251116220311.0981-13-8958-610.1007/978-981-13-8958-0(CKB)4100000009451822(DE-He213)978-981-13-8958-0(MiAaPQ)EBC5889016(PPN)260305669(iGPub)SPNA0064365(EXLCZ)99410000000945182220190831d2019 u| 0engurnn#008mamaatxtrdacontentcrdamediacrrdacarrierClinical Epigenetics /edited by Luke B. Hesson, Antonia L. Pritchard1st ed. 2019.Singapore :Springer Singapore :Imprint: Springer,2019.1 online resource (XI, 265 p. 34 illus., 8 illus. in color.)981-13-8957-8 Includes bibliographical references and index.Genetics and epigenetics: a Historical Overview -- The DNA methylation machinery -- Methylcytosine and its oxidised derivatives -- The role of nucleosomes in epigenetic gene regulation -- Circular RNAs in human health and disease -- The role of histone variants in cancer -- DNA methylation and carcinogenesis: Current and future perspectives -- Dysregulation of cis-regulatory elements in cancer -- Germline epigenetic testing of imprinting disorders in a diagnostic setting -- Cancer methylation biomarkers in circulating cell-free DNA -- The clinical utility of epigenetics.In genetic pathology, epigenetic testing is rare and under utilised. In this book, we introduce epigenetics to a non-expert scientific audience and describe current and future clinical utility of epigenetic testing. By focussing on epigenetics in human disease this book will guide professionals (scientists and clinicians) to understand how epigenetics is relevant in a clinical context, and to implement epigenetic testing in diagnostic laboratories. The book begins with a historical perspective of genetics and epigenetics and describes the work of pioneers who have helped shape these fields. The various mechanisms by which epigenetics can regulate the function of the genome is described. These include DNA methylation, histone modifications, histone variants, nucleosome positioning, cis-regulatory elements, non-coding RNAs and the three-dimensional organisation of chromatin in the nucleus. These are discussed in the context of embryological development, cancer and imprinting disorders, and include examples of epigenetic changes that can be used in diagnosis, prediction of therapeutic response, prognostication or disease monitoring. Finally, for those wishing to implement epigenetic testing in a diagnostic setting, the book includes a case study that illustrates the clinical utility of epigenetic testing.Gene expressionMedical geneticsGene therapyCytogeneticsMolecular biologyGene Expressionhttps://scigraph.springernature.com/ontologies/product-market-codes/B12010Gene Functionhttps://scigraph.springernature.com/ontologies/product-market-codes/B12030Gene Therapyhttps://scigraph.springernature.com/ontologies/product-market-codes/B12020Cytogeneticshttps://scigraph.springernature.com/ontologies/product-market-codes/B12040Molecular Medicinehttps://scigraph.springernature.com/ontologies/product-market-codes/B1700XGene expression.Medical genetics.Gene therapy.Cytogenetics.Molecular biology.Gene Expression.Gene Function.Gene Therapy.Cytogenetics.Molecular Medicine.611.01816Hesson Luke B.edthttp://id.loc.gov/vocabulary/relators/edtPritchard Antonia L.edthttp://id.loc.gov/vocabulary/relators/edtBOOK9910350350303321Clinical epigenetics1908812UNINA