03455nam 22006735 450 991030414260332120200920070455.03-658-08269-010.1007/978-3-658-08269-7(CKB)3710000000311787(EBL)1967759(SSID)ssj0001407838(PQKBManifestationID)11814127(PQKBTitleCode)TC0001407838(PQKBWorkID)11413027(PQKB)10279829(DE-He213)978-3-658-08269-7(MiAaPQ)EBC1967759(PPN)183151445(EXLCZ)99371000000031178720141205d2015 u| 0engur|n|---|||||txtccrPredicting Transcription Factor Complexes A Novel Approach to Data Integration in Systems Biology /by Thorsten Will1st ed. 2015.Wiesbaden :Springer Fachmedien Wiesbaden :Imprint: Springer Spektrum,2015.1 online resource (155 p.)BestMasters,2625-3577Description based upon print version of record.3-658-08268-2 Includes bibliographical references.Protein Complex Prediction -- Protein-Protein Interaction Networks -- Domain-Domain Interaction Networks -- Combinatorial Algorithms -- Algorithm Engineering.In his master thesis Thorsten Will proposes the substantial information content of protein complexes involving transcription factors in the context of gene regulatory  networks, designs the first computational approaches to predict such complexes as well as their regulatory function and verifies the practicability using data of the well-studied yeast S.cereviseae. The novel insights offer extensive capabilities towards a better understanding of the combinatorial control driving transcriptional regulation. Contents Protein Complex Prediction Protein-Protein Interaction Networks Domain-Domain Interaction Networks Combinatorial Algorithms Algorithm Engineering  Target Groups Computational biologists and biologists working with gene regulatory networks Computer scientists interested in biological issues  The Author Currently, the author is pursuing his Ph.D. at the Center for Bioinformatics in Saarbrücken, Germany.  .BestMasters,2625-3577BioinformaticsBioinformatics Computational biology BiomathematicsBioinformaticshttps://scigraph.springernature.com/ontologies/product-market-codes/L15001Computer Appl. in Life Scienceshttps://scigraph.springernature.com/ontologies/product-market-codes/L17004Mathematical and Computational Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/M31000Bioinformatics.Bioinformatics .Computational biology .Biomathematics.Bioinformatics.Computer Appl. in Life Sciences.Mathematical and Computational Biology.570570.285570285Will Thorstenauthttp://id.loc.gov/vocabulary/relators/aut991433BOOK9910304142603321Predicting Transcription Factor Complexes2268957UNINA