01176cam0 22003131 450 SOBE0008078020240910135142.0978884592050920240910d2006 |||||ita|0103 baitaITPsiche e naturaWolfgang Paulia cura di Giuseppe TrautteurMilanoAdelphi2006176 p.ill.22 cmBiblioteca Scientifica40Traduzione a cura di Maurizio Bruno e Laura Benzi001LAEC000162192001 *Biblioteca Scientifica40Moderne beispiele zur "Hintergrundsphysik"SOBA000314624297035Pauli, WolfgangSOBA00031461070310644Trautteur, GiuseppeA600200062947070ITUNISOB20240910RICAUNISOBUNISOB000|Coll|66|K181708SOBE00080780M 102 Monografia moderna SBNM000|Coll|66|K000023SI1817082024090915AcquistoV15SpinosaUNISOBUNISOB20240910135108.020240910135142.0SpinosaModerne beispiele zur "Hintergrundsphysik"4297035UNISOB03497nam 22004935 450 991030045190332120251116191253.0981-10-5336-710.1007/978-981-10-5336-8(CKB)4100000000587413(DE-He213)978-981-10-5336-8(MiAaPQ)EBC5049902(PPN)204532019(EXLCZ)99410000000058741320170918d2018 u| 0engurnn#008mamaatxtrdacontentcrdamediacrrdacarrierAntibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill /edited by Andrew A. Udy, Jason A. Roberts, Jeffrey Lipman1st ed. 2018.Singapore :Springer Singapore :Imprint: Adis,2018.1 online resource (X, 275 p. 22 illus., 9 illus. in color.)981-10-5335-9 Includes bibliographical references.1. Basic Pharmacokinetic Principles -- 2. Antibiotic Pharmacodynamics -- 3. Physiological Manifestations of Critical Illness -- 4. Dosing in Obese Critically Ill Patients -- 5. Hypoalbuminemia and Altered Protein Binding -- 6. Antibacterial Pharmacokinetic/Pharmacodynamic Considerations in the Critically ill -- 7. Augmented Renal Clearance -- 8. Antibiotic Dosing During Extracorporeal Membrane Oxygenation -- 9. Therapeutic Drug Monitoring: More than Avoiding Toxicity -- 10. Generic and Optimised Antibacterial Dosing Strategies in the Critically Ill -- 11. Antifungal PK/PD in the Critically Ill -- 12. Antibiotic Dosing in Pediatric Critically Ill Patients -- 13. Antibiotic Stewardship in the Intensive Care Unit.This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the clinical course in ICU.  Early, appropriate application of antibiotic therapy remains a cornerstone of effective management. However, this is challenging in the critical care environment, given the significant changes in patient physiology and organ function frequently encountered. Being cognisant of these factors, prescribers need to consider modified dosing regimens, not only to ensure adequate drug exposure, and therefore the greatest chance of clinical cure, but also to avoid encouraging drug resistance.ChemotherapyPharmaceutical technologyPharmacotherapyhttps://scigraph.springernature.com/ontologies/product-market-codes/H69000Pharmaceutical Sciences/Technologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B21010Chemotherapy.Pharmaceutical technology.Pharmacotherapy.Pharmaceutical Sciences/Technology.615.1Udy Andrew A.edthttp://id.loc.gov/vocabulary/relators/edtRoberts Jason A(Jason Alexander),edthttp://id.loc.gov/vocabulary/relators/edtLipman Jeffreyedthttp://id.loc.gov/vocabulary/relators/edtBOOK9910300451903321Antibiotic Pharmacokinetic1963855UNINA