04351nam 22008295 450 991030040380332120200705071206.03-319-22066-710.1007/978-3-319-22066-6(CKB)3710000000463309(EBL)3568236(SSID)ssj0001546952(PQKBManifestationID)16141369(PQKBTitleCode)TC0001546952(PQKBWorkID)14796330(PQKB)11755804(DE-He213)978-3-319-22066-6(MiAaPQ)EBC3568236(PPN)18846218X(EXLCZ)99371000000046330920150808d2015 u| 0engur|n|---|||||txtccrUltrafast Dynamics of Phospholipid-Water Interfaces Studied by Nonlinear Time-Resolved Vibrational Spectroscopy /by René Costard1st ed. 2015.Cham :Springer International Publishing :Imprint: Springer,2015.1 online resource (112 p.)Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053"Doctoral Thesis accepted by Max-Born-Institut, Berlin, Germany."3-319-22065-9 Includes bibliographical references at the end of each chapters.Introduction -- Vibrational Spectroscopy -- Ultrafast Vibrational Dynamics of Phospholipid Hydration Sites -- Ultrafast Vibrational Dynamics of Phospholipid Hydration Shells -- Conclusions -- Appendix: Experimental Pulse Parameters.This thesis presents a highly innovative study of the ultrafast structural and vibrational dynamics of hydrated phospholipids, the basic constituents of cell membranes. As a novel approach to the water-phospholipid interface, the author studies phosphate vibrations using the most advanced methods of nonlinear vibrational spectroscopy, including femtosecond two-dimensional infrared spectroscopy. He shows for the first time that the structure of interfacial water undergoes very limited fluctuations on a 300 fs time scale and that the lifetimes of hydrogen bonds with the phospholipid are typically longer than 10 ps. Such properties originate from the steric hindrance of water fluctuations at the interface and the orienting action of strong electric fields from the phospholipid head group dipoles. In an extensive series of additional experiments, the vibrational lifetimes of the different vibrations and the processes of energy dissipation are elucidated in detail.Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053BiophysicsBiophysicsChemistry, Physical and theoreticalCell membranesAtomic structureMolecular structureSpectrum analysisMicroscopyBiological and Medical Physics, Biophysicshttps://scigraph.springernature.com/ontologies/product-market-codes/P27008Physical Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C21001Membrane Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L16050Atomic/Molecular Structure and Spectrahttps://scigraph.springernature.com/ontologies/product-market-codes/P24017Spectroscopy and Microscopyhttps://scigraph.springernature.com/ontologies/product-market-codes/P31090Biophysics.Biophysics.Chemistry, Physical and theoretical.Cell membranes.Atomic structure.Molecular structure.Spectrum analysis.Microscopy.Biological and Medical Physics, Biophysics.Physical Chemistry.Membrane Biology.Atomic/Molecular Structure and Spectra.Spectroscopy and Microscopy.591.19247Costard Renéauthttp://id.loc.gov/vocabulary/relators/aut792805MiAaPQMiAaPQMiAaPQBOOK9910300403803321Ultrafast Dynamics of Phospholipid-Water Interfaces1780144UNINA