00898nam0 2200313 450 00001628320181016124635.020080918d1973----km-y0itay50------baitarusITy-------001yy<<L'>>uomo e l'ambienteA. I. Berg ... [et al.]RomaEditori riuniti1973175 p.19 cmArgomenti29Trad. di: C. Masetti.2001ArgomentiUomo e ambiente naturaleProtezione della naturaEcologiaSaggiUomo e natura500.117Scienze naturali500.118Scienze naturaliBerg,A. I.ITUNIPARTHENOPE20080918RICAUNIMARC000016283333/10620173NAVA4Uomo e l'ambiente273189UNIPARTHENOPE04477nam 22006975 450 991030006970332120200630020216.03-642-38765-910.1007/978-3-642-38765-4(CKB)3710000000074771(EBL)1592755(SSID)ssj0001067716(PQKBManifestationID)11666529(PQKBTitleCode)TC0001067716(PQKBWorkID)11091913(PQKB)10515154(MiAaPQ)EBC1592755(DE-He213)978-3-642-38765-4(PPN)176112758(EXLCZ)99371000000007477120131125d2014 u| 0engur|n|---|||||txtccrMosaicism in Human Skin Understanding Nevi, Nevoid Skin Disorders, and Cutaneous Neoplasia /by Rudolf Happle1st ed. 2014.Berlin, Heidelberg :Springer Berlin Heidelberg :Imprint: Springer,2014.1 online resource (234 p.)Description based upon print version of record.3-642-38764-0 Includes bibliographical references and index.PATTERNS AND MECHANISMS: Mosaicism as a Biological Concept: -- History -- Mosaicism in Plants, Animals, Humans -- Mosaicism Versus Chimerism -- The Mechanisms of Mosaicism -- Genomic Mosaicism of Autosomes -- Epigenetic Mosaicism of autosomes -- Genomic Mosaicism of X Chromosomes -- Epigenetic Mosaicism of X Chromosomes -- The patterns of Mosaicism -- Lines of Blaschko -- Checkerboard Pattern -- Phylloid Pattern -- Patchy Pattern Without Midline Separation -- Lateralization -- Other Patterns, so far Unclassifiable -- MOSAIC SKIN DISORDERS: Nevi -- Melanocytic Nevi -- Other Forms of Pigmentary Mosaicism -- Epidermal Nevi -- Vascular Nevi -- Connective Tissue Nevi -- Nevoid Skin Disorders -- Lyonization (Functional X-Chromosome Mosaicism) in X-Linked Skin Disorders -- Autosomal Non-Nevi -- Neoplastic Skin Lesions -- Benign Tumors -- Malignant Tumors -- CONCLUSION.Mosaicism is a powerful biologic concept, originally developed from the study of plants and animals, and is the necessary basis for the explanation of numerous human skin disorders.   This lavishly illustrated book presents, for the first time, a comprehensive overview of the strikingly manifold patterns and peculiarities of mosaic skin disorders. It is structured in a straightforward, reader-friendly way that will help the dermatologist to understand the underlying molecular mechanisms of skin disorders in order to further improve the treatment outcome. The first two parts of the book are devoted to the mechanisms and patterns of cutaneous mosaicism, with explanation of genomic and epigenetic mosaicism and description of the six archetypal patterns, including the lines of Blaschko, as well as less well defined or as yet unclassifiable patterns. In the third part, the various mosaic skin disorders are examined in depth, including nevi, allelic and non-allelic didymosis, other binary genodermatoses, mosaic manifestations of autosomal dominant skin disorders, and nevoid skin disorders. The book concludes with a note on neoplastic skin lesions, examining models of tumorigenesis.DermatologyPediatricsHuman geneticsNeurologyOphthalmologyDermatologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H1900XPediatricshttps://scigraph.springernature.com/ontologies/product-market-codes/H49006Human Geneticshttps://scigraph.springernature.com/ontologies/product-market-codes/B12008Neurologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H36001Ophthalmologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H44004Dermatology.Pediatrics.Human genetics.Neurology.Ophthalmology.Dermatology.Pediatrics.Human Genetics.Neurology.Ophthalmology.616.5Happle Rudolfauthttp://id.loc.gov/vocabulary/relators/aut755408BOOK9910300069703321Mosaicism in Human Skin2982867UNINA