03705nam 22006255 450 991029989680332120200629183851.03-319-69059-010.1007/978-3-319-69059-9(CKB)4100000001041451(DE-He213)978-3-319-69059-9(MiAaPQ)EBC5149408(PPN)221247203(EXLCZ)99410000000104145120171115d2018 u| 0engurnn#008mamaatxtrdacontentcrdamediacrrdacarrierAcute and Chronic Neural Stimulation via Mechano-Sensitive Ion Channels /by Andy Kah Ping Tay1st ed. 2018.Cham :Springer International Publishing :Imprint: Springer,2018.1 online resource (XVII, 119 p. 33 illus., 32 illus. in color.)Springer Theses, Recognizing Outstanding Ph.D. Research,2190-50533-319-69058-2 Includes bibliographical references at the end of each chapters.Micro- and Nano-Technologies to Probe Brain Mechanobiology -- Acute Neural Stimulation -- Chronic Neural Stimulation -- Phenotypic Selection of Magnetospirillum magneticum (AMB-1) Over-Producers using Magnetic Ratcheting -- Magnetic Microfluidic Separation for Estimating the Magnetic Contents of Magnetotactic Bacteria -- Outlook for Magnetic Neural Stimulation Techniques. .This book describes the tools, developed by the author, for perturbing endogenous mechano-sensitive ion channels for magneto-mechanical neuro-modulation. He explores the ways in which these tools compare against existing ones such as electricity, chemicals, optogenetics, and techniques like thermos/magneto-genetics. The author also reports on two platforms—magnetic ratcheting and magnetic microfluidics for directed evolution and high throughput culture of magnetotactic bacteria—that produce high quality magnetic nanoparticles for biomedical applications like neural stimulations. This thesis was submitted to and approved by the University of California, Los Angeles. Introduces technology for non-invasive control of neural activities that offer deep tissue penetration and controllable dosage; Examines the effects of biomechanical forces on cellular functions; Explores how to improve the reproducibility and uptake of magnetic tools for non-invasive neural modulation.Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053Biomedical engineeringNanotechnologyNanoscienceNanoscienceNanostructuresBiomedical Engineering and Bioengineeringhttps://scigraph.springernature.com/ontologies/product-market-codes/T2700XNanotechnologyhttps://scigraph.springernature.com/ontologies/product-market-codes/Z14000Nanoscale Science and Technologyhttps://scigraph.springernature.com/ontologies/product-market-codes/P25140Biomedical engineering.Nanotechnology.Nanoscience.Nanoscience.Nanostructures.Biomedical Engineering and Bioengineering.Nanotechnology.Nanoscale Science and Technology.616.804645Tay Andy Kah Pingauthttp://id.loc.gov/vocabulary/relators/aut1065055MiAaPQMiAaPQMiAaPQBOOK9910299896803321Acute and Chronic Neural Stimulation via Mechano-Sensitive Ion Channels2542810UNINA