01004cam0-22003851i-450-99000003468040332120100903150833.0000003468FED01000003468(Aleph)000003468FED0100000346820020821d1959----km-y0itay50------baitaengITy-------001yy<<La >>conducibilità elettroliticaRaymond M. Fuoss, Filippo AccascinaRomaEdizioni dell'Ateneo1959X, 291 p.23 cm001000921560Chimica fisica660.29541660Fuoss,Raymond M.Accascina,FilippoITUNINARICAUNIMARCBK99000003468040332113 B 03 1223998FINBC36B-11417353FI104 140-27ELETTR. 2822DINCHFINBCFI1DINCHUNINA05220nam 2200625Ia 450 991043762150332120200520144314.01-4614-7940-110.1007/978-1-4614-7940-6(CKB)2670000000400681(EBL)1317800(OCoLC)854976218(SSID)ssj0000958043(PQKBManifestationID)11958415(PQKBTitleCode)TC0000958043(PQKBWorkID)10985340(PQKB)10016404(DE-He213)978-1-4614-7940-6(MiAaPQ)EBC1317800(PPN)17242027X(EXLCZ)99267000000040068120130619d2013 uy 0engur|n|---|||||txtccrEndocannabinoid regulation of monoamines in psychiatric and neurological disorders /Elisabeth J. Van Bockstaele, editor1st ed. 2013.New York Springer20131 online resource (340 p.)Description based upon print version of record.1-4899-9608-7 1-4614-7939-8 Includes bibliographical references and index.Endocannabinoids and monoamines: modulating the modulators -- Endocannabinoid-mediated synaptic plasticity -- Current cannabinoid receptor nomenclature and pharmacological principles -- Cue-elicited craving for cannabis activates the reward neurocircuitry associated with the neuropathology of addiction -- Cannabinoid modulation of dopaminergic circuits in neurodegenerative and neuropsychiatric disorders -- Pathophysiology of mood disorders and mechanisms of action of antidepressants and mood stabilizers -- Anatomical, biochemical and behavioral evidence for cannabinoid modulation of noradrenergic circuits: role of norepinephrine in cannabinoid-induced aversion -- Gender Disparity of Depression: The Role of Endocannabinoids and Noradrenergic Function -- Endocannabinoids, Monoamines and Stress -- Chronic effects of cannabinoid drugs on monoaminergic systems and the role of endocannabinoids and cannabinoid receptors in human brain disorders -- Endocannabinoid Signaling and the Regulation of the Serotonin System -- Modulation of serotonin firing activity through CB1 agonists and FAAH inhibitors -- Involvement of serotonergic system in cannabinoid analgesia -- Cannabinoids, monoamines, COMT and schizophrenia: pathobiological mechanisms in psychosis.The past two decades have seen a tremendous growth in knowledge related to cannabinoid receptor signaling in brain.  In addition, the impact and consequences of cannabinoid modulation of monoaminergic circuits is steadily emerging demonstrating a significant interaction between these two systems in a variety of psychiatric (affective disorders) and neurological disorders (multiple sclerosis, pain). Despite increasing evidence from preclinical data suggesting that therapeutic use of cannabinoid-based drugs may outweigh any potential risks in certain serious medical conditions, the debate surrounding its widespread utility continues as regulatory concerns preclude a smooth transition of promising preclinical studies into clinical trial testing. This may persist in the near future as state and federal governments debate over regulation of medicinal applications of cannabis. Applications for medicinal cannabinoids that are already under investigation include the treatment of nausea, anorexia, neurodegeneration, inflammation, excitotoxicity and pain. The appetitive and anti-emetic properties of cannabinoids have led to the approval of their use in chemotherapy and AIDS patients.  There is growing evidence for therapeutic cannabinoid effects on inflammatory and excitotoxic cellular processes that are linked to epilepsy, Parkinson’s disease, amyotrophic lateral sclerosis, spasticity, and central nervous system injury. The chapters, herein, review and discuss current insights into the brain endocannabinoid system, cannabinoid receptor signaling on synaptic plasticity, potential therapeutic applications with a particular focus on endocannabinoid modulation of dopaminergic, noradrenergic and serotonergic circuitry. The potential for establishing cannabinoid-monoaminergic interactions as a novel target in the development of improved treatment strategies for psychiatric and neurological disorders is promising and will require future clinical studies to determine whether promising pre-clinical findings translate into new therapies.CannabinoidsTherapeutic usePsychopharmacologyNervous systemDiseasesTreatmentCannabinoidsTherapeutic use.Psychopharmacology.Nervous systemDiseasesTreatment.610612.8612.8042616.8Van Bockstaele Elisabeth J1762501MiAaPQMiAaPQMiAaPQBOOK9910437621503321Endocannabinoid regulation of monoamines in psychiatric and neurological disorders4202482UNINA02117oam 2200589zu 450 991013417780332120241212214929.0(CKB)111026746731840(SSID)ssj0000558182(PQKBManifestationID)12289797(PQKBTitleCode)TC0000558182(PQKBWorkID)10559496(PQKB)10981689(Association for Computing Machinery)10.5555/62597(EXLCZ)9911102674673184020160829d1988 uy engurnn|008mam|atxtccrDatabases in Parallel and Distributed Systems, 1988 International Symposium on: Proceedings[Place of publication not identified]IEEE Computer Society Press19881 online resource (221 p.;) ACM ConferencesBibliographic Level Mode of Issuance: Monograph9780818608933 0818608935 ACM ConferencesDPDS '88Database managementCongressesParallel processing (Electronic computers)CongressesElectronic data processingDistributed processingCongressesEngineering & Applied SciencesHILCCComputer ScienceHILCCDatabase managementCongressesParallel processing (Electronic computers)Electronic data processingDistributed processingCongressesEngineering & Applied SciencesComputer Science005.74Silberschatz AbrahamKim WonJajodia SushilSigarch,IEEE Computer Society.Technical Committee on Data Base Engineering,International Symposium on Databases in Parallel and Distributed Systems.PQKBBOOK9910134177803321Databases in Parallel and Distributed Systems, 1988 International Symposium on: Proceedings2188581UNINA05965nam 22007095 450 991029861330332120260102194856.01-4939-2346-310.1007/978-1-4939-2346-5(CKB)3710000000343628(EBL)1973888(SSID)ssj0001424263(PQKBManifestationID)11748687(PQKBTitleCode)TC0001424263(PQKBWorkID)11362987(PQKB)11402685(DE-He213)978-1-4939-2346-5(MiAaPQ)EBC1973888(PPN)183518691(EXLCZ)99371000000034362820150128d2015 u| 0engur|n|---|||||txtccrDetection and Typing Strategies for Pathogenic Escherichia coli /by Lucia Rivas, Glen E. Mellor, Kari Gobius, Narelle Fegan1st ed. 2015.New York, NY :Springer New York :Imprint: Springer,2015.1 online resource (114 p.)SpringerBriefs in Food, Health, and Nutrition,2197-5728Description based upon print version of record.1-4939-2345-5 Includes bibliographical references.Chapter 1 Introduction to Pathogenic Escherichia coli -- 1.1 Pathotypes of Escherichia coli causing diarrhoeal diseases -- 1.2 Escherichia coli -- 1.3 Pathogenic types of E. coli -- 1.4 Shiga toxin-producing and Enterohemorrhagic E. coli -- 1.4.1    Virulence determinants of Shiga-toxin producing E. coli -- 1.4.2 Shiga-toxin producing E. coli-mediated disease -- 1.4.3 Epidemiology of Shiga toxin-producing E. coli -- 1.4.4    Ecology of Shiga-toxin producing E. coli -- 1.4.5 Transmission of Shiga-toxin producing E. coli -- 1.4.6 Shiga-toxin producing E. coli occurrence in foods -- 1.5 Enterotoxigenic E. coli -- 1.6 Enteropathogenic E. coli -- 1.7 Enteroinvasive E. coli -- 1.8 Enteroaggregative and Diffusely Adherent E. coli..-1.9 References -- Chapter 2 Isolation and detection of pathogenic Escherichia coli in foods -- 2.1 Introduction -- 2.2 General method of isolation for E. coli -- 2.3 Shiga toxin-producing E. coli -- 2.3.1 Culture and isolation of Shiga toxin-producing E. coli -- 2.3.2    Molecular detection of Shiga toxin-producing E. coli -- 2.4 Enumeration of Shiga toxin-producing E.coli -- 2.5 Immunological detection methods for pathogenic E. coli -- 2.6 Cell culture assays used for pathogenic E. coli -- 2.6.1 Cell cytotoxicity assay for Shiga toxin-producing E. coli -- 2.6.2    Cell adherence assays -- 2.7 Enteroinvasive E. coli -- 2.8 Enterotoxigenic E. coli -- 2.9 Enteropathogenic E. coli -- 2.10     Enteroaggregative E. coli and Diffusely Adherent E. coli -- 2.11 References -- Chapter 3 Typing and Subtyping methods for pathogenic Escherichia coli -- 3.1 Introduction -- 3.2 Biochemical profiling -- 3.3 Serotyping -- 3.4 Phage typing -- 3.5 Multilocus enzyme electrophoresis -- 3.6 Multilocus sequencetyping -- 3.7 Pulsed-field gel electrophoresis -- 3.8 Multiple-locus variable number tandem repeat analysis -- 3.9 Repetitive element palindromic polymerase chain reaction -- 3.10 Random amplified polymorphic DNA -- 3.11 Shiga toxin subtypes and bacteriophage insertion sites -- 3.12 Lineage specific polymorphism analysis -- 3.13 Whole genome sequencing -- 3.14 -- References -- Chapter 4 Emerging and future trends and technologies for the detection and typing of Escherichia coli -- 4.1 Future trends in foodborne illness and E. coli -- 4.2 Future trends in the detection and typing of pathogens -- 4.2.1 Microarrays -- 4.2.2 Matrix Assisted Laser-Desorption Ionization-Time-Of-Flight Mass Spectrometry -- 4.2.3 Nanotechnology -- 4.2.4 Next-generating sequencing of the whole bacterial genome -- 4.3 References.This Brief will review the methods that are currently available for the detection, isolation, and typing of pathogenic E. coli with a particular focus on foodborne diseases caused by the Shiga toxigenic E. coli group, which have been implicated in a number of significant outbreaks in recent years. Pathogenic forms of E. coli can cause a variety of diarrheal diseases in hosts due to the presence of specific colonization and virulence factors, and pathogenicity-associated genes, which are generally not present in other E. coli. Six pathotypes of pathogenic E. coli are recognized (Shiga toxigenic E. coli, Enteropathogenic E. coli, Enterotoxigenic E. coli, Enteroinvasive E. coli, Enteroaggregative E. coli and Diffusely Adherent E. coli) and certain strains among these groups are major public health concerns due to the severity of disease that they can cause. Methods to detect and isolate these pathogens from a variety of sources are constantly evolving. In addition, the accumulation of knowledge on these pathogens allows for improved intervention strategies.SpringerBriefs in Food, Health, and Nutrition,2197-5728Food scienceBacteriaIndustrial microbiologyFood ScienceBacteriaIndustrial MicrobiologyFood science.Bacteria.Industrial microbiology.Food Science.Bacteria.Industrial Microbiology.54579.3641.3660.62664Rivas Luciaauthttp://id.loc.gov/vocabulary/relators/aut925440Mellor Glen Eauthttp://id.loc.gov/vocabulary/relators/autGobius Kariauthttp://id.loc.gov/vocabulary/relators/autFegan Narelleauthttp://id.loc.gov/vocabulary/relators/autBOOK9910298613303321Detection and Typing Strategies for Pathogenic Escherichia coli2077938UNINA