03374nam 22006135 450 991029859730332120250609110858.03-319-77095-010.1007/978-3-319-77095-6(CKB)4100000002892488(MiAaPQ)EBC5441117(DE-He213)978-3-319-77095-6(PPN)225548712(MiAaPQ)EBC5595529(EXLCZ)99410000000289248820180314d2018 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierInvestigation of Nanoscopic Dynamics and Potentials by Interferometric Scattering Microscopy /by Jaime Ortega Arroyo1st ed. 2018.Cham :Springer International Publishing :Imprint: Springer,2018.1 online resource (168 pages)Springer Theses, Recognizing Outstanding Ph.D. Research,2190-50533-319-77094-2 Introduction -- Non-fluorescent single-molecule approaches to optical microscopy -- Experimental Methods -- Anomalous diffusion due to interleaflet coupling and molecular pinning -- Structural dynamics of myiosin 5a -- All optical label-free detection, imaging and tracking of single proteins -- Single-molecule chemical dynamics: direct observation of physical autocatalysis -- Outlook.This thesis offers a unique guide to the development and application of ultrasensitive optical microscopy based on light scattering. Divided into eight chapters, it covers an impressive range of scientific fields, from basic optical physics to molecular biology and synthetic organic chemistry. Especially the detailed information provided on how to design, build and implement an interferometric scattering microscope, as well as the descriptions of all instrumentation, hardware interfacing and image processing necessary to achieve the highest levels of performance, will be of interest to researchers now entering the field.Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053Chemistry, Physical and theoreticalChemistry, OrganicCytologyAtomsPhysicsPhysical Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C21001Organic Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C19007Cell Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L16008Atomic, Molecular, Optical and Plasma Physicshttps://scigraph.springernature.com/ontologies/product-market-codes/P24009Chemistry, Physical and theoretical.Chemistry, Organic.Cytology.Atoms.Physics.Physical Chemistry.Organic Chemistry.Cell Biology.Atomic, Molecular, Optical and Plasma Physics.547 Ortega Arroyo Jaimeauthttp://id.loc.gov/vocabulary/relators/aut768302BOOK9910298597303321Investigation of Nanoscopic Dynamics and Potentials by Interferometric Scattering Microscopy1564858UNINA