03278nam 22005895 450 991029845460332120200702124749.03-319-19791-610.1007/978-3-319-19791-3(CKB)3710000000532211(EBL)4182262(SSID)ssj0001583895(PQKBManifestationID)16263694(PQKBTitleCode)TC0001583895(PQKBWorkID)14864558(PQKB)11300595(DE-He213)978-3-319-19791-3(MiAaPQ)EBC4182262(PPN)190525746(EXLCZ)99371000000053221120151129d2015 u| 0engur|n|---|||||txtccrSertoli Cell Metabolism and Spermatogenesis /by Pedro F. Oliveira, Marco G. Alves1st ed. 2015.Cham :Springer International Publishing :Imprint: Springer,2015.1 online resource (103 p.)SpringerBriefs in Cell Biology,2625-3534Description based upon print version of record.3-319-19790-8 Includes bibliographical references.1 Introductory remarks -- 2 The Sertoli cell at a glance -- 3 Spermatogenesis -- 4 Sertoli cell and germ cell differentiation -- 5 Testicular Metabolic Cooperation -- 6 Modulation of Sertoli cell metabolism -- 7 Concluding remarks -- 8 Acknowledgments -- 9 References.This book is focused on Sertoli cell physiology and its role in the spermatogenic event. These cells, known as “nurse cells”, are essential for the normal development of germ cells by offering not only physical support and creating an immune-privileged environment, but also for providing nutritional support. The presence of Sertoli cells promotes the establishment of the appropriate microenvironment so that spermatogenesis may occur. Spermatogenesis maintenance in vivo is highly dependent on the metabolic cooperation established between Sertoli cells and developing germ cells. For many years this metabolic cooperation between testicular cells has been disregarded, but recent advances have highlighted the relevance of these processes for male fertility. Thus, the understanding of the functioning and regulation of these metabolic processes is a crucial step to identify key mechanisms associated with Sertoli cell (dys)function and to enlighten their influence on male fertility.SpringerBriefs in Cell Biology,2625-3534MedicineCell cultureBiomedicine, generalhttps://scigraph.springernature.com/ontologies/product-market-codes/B0000XCell Culturehttps://scigraph.springernature.com/ontologies/product-market-codes/L16020Medicine.Cell culture.Biomedicine, general.Cell Culture.610Oliveira Pedro Fauthttp://id.loc.gov/vocabulary/relators/aut1062564Alves Marco Gauthttp://id.loc.gov/vocabulary/relators/autBOOK9910298454603321Sertoli Cell Metabolism and Spermatogenesis2526667UNINA