01695nam 2200541 450 991015488730332120200520144314.01-78785-645-31-118-92398-7(CKB)4330000000007504(MiAaPQ)EBC4756293(Au-PeEL)EBL4756293(CaPaEBR)ebr11309811(CaONFJC)MIL974562(OCoLC)965774127(EXLCZ)99433000000000750420161216h20172017 uy 0engurcnu||||||||rdacontentrdamediardacarrierThe handbook of the criminology of terrorism /edited by Gary LaFree, Joshua D. FreilichChichester, West Sussex, England :Wiley-Blackwell,2017.©20171 online resource (630 pages) illustrationsWiley Handbooks in Criminology and Criminal Justice1-118-92396-0 1-118-92395-2 Includes bibliographical references at the end of each chapters and index.Wiley handbooks in criminology and criminal justice.CriminologyTerrorismResearchTerrorismPreventionElectronic books.Criminology.TerrorismResearch.TerrorismPrevention.364.1317LaFree Gary878242Freilich Joshua D.MiAaPQMiAaPQMiAaPQBOOK9910154887303321The handbook of the criminology of terrorism2287555UNINA03802nam 2200577Ia 450 991043801360332120250610110126.01-4471-4531-310.1007/978-1-4471-4531-8(CKB)3280000000020507(EBL)1698284(OCoLC)847008421(SSID)ssj0000904293(PQKBManifestationID)11479093(PQKBTitleCode)TC0000904293(PQKBWorkID)10919674(PQKB)11704632(DE-He213)978-1-4471-4531-8(MiAaPQ)EBC1698284(PPN)170486885(MiAaPQ)EBC29095561(EXLCZ)99328000000002050720111102d2013 uy 0engur|n|---|||||txtccrThe heart of Leonardo /Francis C. Wells1st ed. 2013.London Springer-Verlag20131 online resource (277 p.)Description based upon print version of record.1-4471-4530-5 Includes bibliographical references and index.Foreword by HRH Prince Charles, The Prince of Wales -- Foreword by Martin Kemp -- Preface -- Acknowledgements -- Introduction -- The Making of a Master: Leonardo, His Life and Times -- Leonardo, Anatomist or Natural Philosopher? -- Leonardo’s Use of Drawing -- Leonardo Da Vinci Drawings -- Leonardo’s Heart -- Leonardo: A Personal Legacy -- Leonardo Scholarship and the Cataloguing of the Anatomical Manuscripts -- Bibliography.The dynamic nature of heart action and the ever changing demands on its output and power make it an organ that can only be understood by integrating form with function at every level. Our contemporary understanding of the human heart and its workings is at the cutting edge of modern medical and biological research but, even in the current era of advanced molecular biology, mathematics and engineering, we still struggle to fully decipher the complexities of the normal and diseased heart. Leonardo’s heart studies represent the pinnacle of his anatomical endeavours. In his work on the heart, his use of ingenious diagrams as well as detailed representational drawings is cleverly combined with carefully crafted verbal descriptions of complicated physiological concepts. Some of his thinking, developed through drawing, was so advanced that only now with the advent of accessible technology and advances in modern knowledge of the heart, it is possible to re-interpret Leonardo’s conclusions and to point out how accurate his logical reasoning and pure observation really was. Several of his ideas continue to sit well alongside our modern understanding of cardiac physiology and heart function. This book will feature all of Leonardo's drawings on the heart and its physiology, accompanied by translations of his accompanying notes. The veracity of Leonardo's work is proven against contemporary dissections of cardiac structure and wherever possible, his illustrations are compared with contemporary images generated by magnetic resonance scanners and high definition ultrasound. It represents the only modern interpretation of Leonardo’s works by a practicing clinician and anatomist in a way that is meaningful to cardiology and medical specialists as well as art historians, and the general public.HeartPhysiologyHeartPhysiology.610611612.17616.12Wells Francis C786383MiAaPQMiAaPQMiAaPQBOOK9910438013603321The heart of Leonardo4192184UNINA04491nam 22006015 450 991029840810332120251116203505.03-319-97421-110.1007/978-3-319-97421-7(CKB)4100000006674651(MiAaPQ)EBC5521333(DE-He213)978-3-319-97421-7(PPN)230542905(EXLCZ)99410000000667465120180920d2018 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierCardiac Extracellular Matrix Fundamental Science to Clinical Applications /edited by Eric G. Schmuck, Peiman Hematti, Amish N. Raval1st ed. 2018.Cham :Springer International Publishing :Imprint: Springer,2018.1 online resource (252 pages)Advances in Experimental Medicine and Biology,0065-2598 ;10983-319-97420-3 Preface -- Biomechanical Properties and Mechanobiology of Cardiac ECM -- Imaging the Cardiac Extracellular Matrix -- Animal Models and Cardiac Extracellular Matrix Research -- Applications of Cardiac Extracellular Ma-trix in Tissue Engineering and Regenera-tive Medicine -- Whole Cardiac Tissue Bioscaffolds -- Natural Sources of Extracellular Matrix for Cardiac Repair -- Cardiac Extracellular Matrix Modification as a Therapeutic Approach -- Extracellular Matrix for Myocardial Repair -- Role of Extracellular Matrix in Cardiac Cellular Therapies -- Regulation of Regenerative Medicine Products -- Clinical Trial Design for Investigational Cardio-Regenerative Therapy -- Regenerative Medicine Venturing at the University-Industry Boundary: Implications for Institutions, Entrepreneurs, and Industry -- Index.This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM’s role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.Advances in Experimental Medicine and Biology,0065-2598 ;1098CytologyCardiologyBiomedical engineeringHeartSurgeryCell Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L16008Cardiologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H33037Biomedical Engineering/Biotechnologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B24000Cardiac Surgeryhttps://scigraph.springernature.com/ontologies/product-market-codes/H59028Cytology.Cardiology.Biomedical engineering.HeartSurgery.Cell Biology.Cardiology.Biomedical Engineering/Biotechnology.Cardiac Surgery.611.0182Schmuck Eric G.edthttp://id.loc.gov/vocabulary/relators/edtHematti Peimanedthttp://id.loc.gov/vocabulary/relators/edtRaval Amish N.edthttp://id.loc.gov/vocabulary/relators/edtBOOK9910298408103321Cardiac Extracellular Matrix2494387UNINA