04444nam 22005895 450 991029839710332120200703102531.03-319-95294-310.1007/978-3-319-95294-9(CKB)4100000007103005(MiAaPQ)EBC5596999(DE-He213)978-3-319-95294-9(PPN)231461380(EXLCZ)99410000000710300520181027d2018 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierBiomechanics in Oncology /edited by Cheng Dong, Nastaran Zahir, Konstantinos Konstantopoulos1st ed. 2018.Cham :Springer International Publishing :Imprint: Springer,2018.1 online resource (xii, 376 pages) illustrationsAdvances in Experimental Medicine and Biology,0065-2598 ;10923-319-95293-5 Includes bibliographical references and index.Biomaterials in Mechano-oncology: Means to Tune Materials to Study Cancer -- Traction Force Microscopy for Non-Invasive Imaging of Cell Forces -- Non-Invasive Imaging: Brillouin Confocal Microscopy -- Exposing Cell-itary Confinement: Understanding The Mechanisms Of Confined Single Cell Migration -- Modeling Cell Migration Mechanics -- Engineered models of metastasis with application to study cancer biomechanics -- Microenvironment influences cancer cell mechanics from tumor growth to metastasis -- From Cancer Immunoediting to New Strategies in Cancer Immunotherapy: The Roles of Immune Cells and Mechanics in Oncology -- Biomechanics of the circulating tumor cell microenvironment -- Mechanics of the cell nucleus -- Mechanical Forces in Tumor Angiogenesis -- DNA Mechanics and Topology -- Design of Fiber Networks for Studying Metastatic Invasion -- Extracellular matrix stiffness exists in a feedback loop that drives tumor progression -- Platelet-Based Drug Delivery for Cancer Applications -- The National Cancer Institute Investment in Biomechanics in Oncology Research.This book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell mechanics, and platelet-based drug delivery for cancer applications. This is an ideal book for graduate students, biomedical engineers, and researchers in the field of mechanobiology and oncology. This book also: Describes how mechanical properties of cancer cells, the extracellular matrix, tumor microenvironment and immuno-editing, and fluid flow dynamics contribute to tumor progression and the metastatic process Provides the latest research on non-invasive imaging, including traction force microscopy and brillouin confocal microscopy Includes insight into NCIs’ role in supporting biomechanics in oncology research Details how biomaterials in mechano-oncology can be used as a means to tune materials to study cancer.Advances in Experimental Medicine and Biology,0065-2598 ;1092Biomedical engineeringCancer researchOncology  Biomedical Engineering/Biotechnologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B24000Cancer Researchhttps://scigraph.springernature.com/ontologies/product-market-codes/B11001Biomedical Engineering and Bioengineeringhttps://scigraph.springernature.com/ontologies/product-market-codes/T2700XOncologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H33160Biomedical engineering.Cancer research.Oncology  .Biomedical Engineering/Biotechnology.Cancer Research.Biomedical Engineering and Bioengineering.Oncology.573.1536Dong Chengedthttp://id.loc.gov/vocabulary/relators/edtZahir Nastaranedthttp://id.loc.gov/vocabulary/relators/edtKonstantopoulos Konstantinosedthttp://id.loc.gov/vocabulary/relators/edtBOOK9910298397103321Biomechanics in Oncology2496867UNINA