03540nam 22006855 450 991029834250332120200629150428.03-319-09414-910.1007/978-3-319-09414-4(CKB)3710000000239436(EBL)1967197(OCoLC)891655201(SSID)ssj0001353636(PQKBManifestationID)11868554(PQKBTitleCode)TC0001353636(PQKBWorkID)11317062(PQKB)10090918(MiAaPQ)EBC1967197(DE-He213)978-3-319-09414-4(PPN)181350726(EXLCZ)99371000000023943620140915d2014 u| 0engur|n|---|||||txtccrHepatocellular Carcinoma Cellular and Molecular Mechanisms and Novel Therapeutic Strategies /by Rajagopal N. Aravalli, Clifford J. Steer1st ed. 2014.Cham :Springer International Publishing :Imprint: Springer,2014.1 online resource (74 p.)SpringerBriefs in Cancer Research,2194-1173Description based upon print version of record.3-319-09413-0 Includes bibliographical references and index.Introduction -- Etiology -- Current diagnosis and treatment options for HCC -- Pathophysiology of HCC -- Molecular mechanisms of HCC -- Animal models of liver cancer -- Novel therapeutic strategies to combat HCC -- Conclusions.This book provides up-to-date information on the development and progression of hepatocellular carcinoma (HCC) with a review of the cellular and molecular mechanisms involved in the disease process. Recent research in HCC has led to significant progress in our understanding of the cellular processes and molecular mechanisms that occur during multi-stage events that lead to hepatocarcinogenesis. The emergence of micro RNAs and molecular targeted therapies have added a new dimension in our efforts to combat this deadly disease, Chapters include discussion and evaluation of current intervention strategies and therapeutic options and a focus on the novel approaches that are being pursued, such as micro-RNA based therapies and personalized medicine to treat liver cancer. This book will be of interest to basic and clinical researchers, as well as to drug developers.SpringerBriefs in Cancer Research,2194-1173Cancer researchOncology  Pharmaceutical technologyCancer Researchhttps://scigraph.springernature.com/ontologies/product-market-codes/B11001Oncologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H33160Pharmaceutical Sciences/Technologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B21010Cancer research.Oncology  .Pharmaceutical technology.Cancer Research.Oncology.Pharmaceutical Sciences/Technology.610614.5999615.19616994Aravalli Rajagopal Nauthttp://id.loc.gov/vocabulary/relators/aut1064276Steer Clifford Jauthttp://id.loc.gov/vocabulary/relators/autBOOK9910298342503321Hepatocellular Carcinoma2537259UNINA