03620nam 22006855 450 991029832300332120200705162346.01-4939-0615-110.1007/978-1-4939-0615-4(CKB)3710000000114082(EBL)1730899(SSID)ssj0001237178(PQKBManifestationID)11737774(PQKBTitleCode)TC0001237178(PQKBWorkID)11249256(PQKB)10135288(MiAaPQ)EBC1730899(DE-He213)978-1-4939-0615-4(PPN)178781770(EXLCZ)99371000000011408220140512d2014 u| 0engur|n|---|||||txtccrCorrelation-based network analysis of cancer metabolism[electronic resource] A new systems biology approach in metabolomics /by Emily G. Armitage, Helen L. Kotze, Kaye J. Williams1st ed. 2014.New York, NY :Springer New York :Imprint: Springer,2014.1 online resource (67 p.)SpringerBriefs in Systems Biology,2193-4746Description based upon print version of record.1-4939-0614-3 Includes bibliographical references.An overview of Cancer metabolism -- Cancer hypoxia and the tumour microenvironment as effectors of cancer metabolism -- Metabolic fingerprinting of in vitro cancer cell samples -- Network-based correlation analysis of metabolic fingerprinting data -- Case study: Systems biology of HIF metabolism in cancer -- Case study: Systems biology of chemotherapy resistance in hypoxic cancer -- Index.With the rise of systems biology as an approach in biochemistry research, using high throughput techniques such as mass spectrometry to generate metabolic profiles of cancer metabolism is becoming increasingly popular. There are examples of cancer metabolic profiling studies in the academic literature; however they are often only in journals specific to the metabolomics community. This book will be particularly useful for post-graduate students and post-doctoral researchers using this pioneering technique of network-based correlation analysis. The approach can be adapted to the analysis of any large scale metabolic profiling experiment to answer a range of biological questions in a range of species or for a range of diseases.SpringerBriefs in Systems Biology,2193-4746Systems biologyMetabolismCancer researchSystems Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L15010Metabolomicshttps://scigraph.springernature.com/ontologies/product-market-codes/L15030Cancer Researchhttps://scigraph.springernature.com/ontologies/product-market-codes/B11001Systems biology.Metabolism.Cancer research.Systems Biology.Metabolomics.Cancer Research.616.994Armitage Emily Gauthttp://id.loc.gov/vocabulary/relators/aut1058249Kotze Helen Lauthttp://id.loc.gov/vocabulary/relators/autWilliams Kaye Jauthttp://id.loc.gov/vocabulary/relators/autMiAaPQMiAaPQMiAaPQBOOK9910298323003321Correlation-based network analysis of cancer metabolism2498395UNINA