04175nam 22006735 450 991029826340332120200704232951.01-4939-2895-310.1007/978-1-4939-2895-8(CKB)3710000000454031(EBL)3567916(SSID)ssj0001534709(PQKBManifestationID)11820809(PQKBTitleCode)TC0001534709(PQKBWorkID)11513903(PQKB)10665578(DE-He213)978-1-4939-2895-8(MiAaPQ)EBC3567916(PPN)187689482(EXLCZ)99371000000045403120150727d2015 u| 0engur|n|---|||||txtccrGlucocorticoid Signaling From Molecules to Mice to Man /edited by Jen-Chywan Wang, Charles Harris1st ed. 2015.New York, NY :Springer New York :Imprint: Springer,2015.1 online resource (387 p.)Advances in Experimental Medicine and Biology,0065-2598 ;872Description based upon print version of record.1-4939-2894-5 Includes bibliographical references at the end of each chapters and index.Section I: Introductory Materials -- Regulatory actions of glucocorticoid hormones: from organisms to mechanisms.-  Molecular Biology of  Glucocorticoid Signaling.-Mechanisms of Glucocorticoid-regulated Gene Transcription -- Clinical Perspective: What do Addison and Cushing tell us about Glucocorticoid Action? -- Section II: Effects of Glucocorticoids in Metabolism -- Regulation of Glucose Homeostasis by Glucocorticoids -- How do Glucocorticoids Regulate Lipid Metabolism? -- Glucocorticoids and Skeletal Muscle -- Section III: Specific Effects of Glucocorticoids on Tissues -- Glucocorticoid- induced osteoporosis -- Effects of Glucocorticoids on Immune System -- Glucocorticoids and the brain: neural mechanisms regulating the stress response -- Glucocorticoid Regulation of Reproduction -- Glucocorticoids and the lung -- Glucocorticoids and the Cardiovascular System -- Glucocorticoids and Cancer -- Section IV: Miscellaneous Topics -- Animal Models of Altered Glucocorticoid Signaling -- The Dehydrogenase Hypothesis -- Conclusions and Future Directions.This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.Advances in Experimental Medicine and Biology,0065-2598 ;872BiochemistryEndocrinologyHuman physiologyBiochemistry, generalhttps://scigraph.springernature.com/ontologies/product-market-codes/L14005Endocrinologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H33053Human Physiologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B13004Biochemistry.Endocrinology.Human physiology.Biochemistry, general.Endocrinology.Human Physiology.612.405Wang Jen-Chywanedthttp://id.loc.gov/vocabulary/relators/edtHarris Charlesedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910298263403321Glucocorticoid Signaling2513392UNINA