03092nam 2200445z- 450 991026113420332120210212(CKB)4100000002484750(oapen)https://directory.doabooks.org/handle/20.500.12854/59364(oapen)doab59364(EXLCZ)99410000000248475020202102d2017 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierSignalling Pathways in Embryonic DevelopmentFrontiers Media SA20171 online resource (177 p.)Frontiers Research Topics2-88945-346-4 The formation of a complex multicellular organism from a single cell is one of the most amazing processes of biology. Embryonic development is characterised by the careful regulation of cellular behaviours such that cells proliferate, migrate, differentiate and form tissues at the correct place and time. These processes are genetically controlled and depend both on the history of cells, their lineage, and on the activities of signalling pathways, which coordinate the cell interactions leading to organogenesis. The aim of the Frontiers research topic "Signalling pathways in embryonic development" has been to provide a forum for experts in cell and developmental biology to share recent advances in the field of signalling during embryonic development. Sixteen articles in a variety of formats are united in this Topic, offering a valuable collection for researchers looking for an update in the knowledge of signalling pathways operating during embryogenesis. The works, focused mainly on vertebrates, explore different aspects of this theme from cell communication to organ formation and have implications for areas as distant as evolution or pathology. Understanding developmental signalling pathways is important for several reasons. It gives us information about basic mechanisms of cell function and interactions needed for morphogenesis and organogenesis. It uncovers the basis of congenital malformations, since errors at any step of cell signalling during development are a major cause of defects. This fundamental insight gives us clues to understand the mechanisms operating in evolution that explain diversity in form and function. And finally, it allows the identification of possible causes of disease in the adult organism (such as cancer or degenerative diseases) pinpointing possible targets for therapeutic approaches.Biology, life sciencesbicsscdevelopmentembryoFgfNotchorganogenesisShhSignallingWntBiology, life sciencesAndrea E. Munsterbergauth1329295Sigmar StrickerauthJuan J. Sanz-EzquerroauthBOOK9910261134203321Signalling Pathways in Embryonic Development3039395UNINA03814nam 22006255 450 991030010280332120200704200325.0978-981-13-0146-9981-13-0146-810.1007/978-981-13-0146-9(CKB)4100000004244361(DE-He213)978-981-13-0146-9(MiAaPQ)EBC5394431(PPN)227400232(EXLCZ)99410000000424436120180512d2018 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierGeneralized Inverses: Theory and Computations /by Guorong Wang, Yimin Wei, Sanzheng Qiao1st ed. 2018.Singapore :Springer Singapore :Imprint: Springer,2018.1 online resource (XIX, 378 p. 6 illus.) Developments in Mathematics,1389-2177 ;53981-13-0145-X Equation Solving Generalized Inverses -- Drazin Inverse -- Generalization of the Cramer's Rule and the Minors of the Generalized Inverses -- Reverse Order and Forward Order Laws for A(2)T,S -- Computational Aspects -- Structured Matrices and Their Generalized Inverses -- Parallel Algorithms for Computing the Generalized Inverses -- Perturbation Analysis of the Moore-Penrose Inverse and the Weighted Moore-Penrose Inverse -- Perturbation Analysis of the Drazin Inverse and the Group Inverse -- Generalized Inverses of Polynomial Matrices -- M-P Inverse of Linear Operators.This book begins with the fundamentals of the generalized inverses, then moves to more advanced topics. It presents a theoretical study of the generalization of Cramer's rule, determinant representations of the generalized inverses, reverse order law of the generalized inverses of a matrix product, structures of the generalized inverses of structured matrices, parallel computation of the generalized inverses, perturbation analysis of the generalized inverses, an algorithmic study of the computational methods for the full-rank factorization of a generalized inverse, generalized singular value decomposition, imbedding method, finite method, generalized inverses of polynomial matrices, and generalized inverses of linear operators. This book is intended for researchers, postdocs, and graduate students in the area of the generalized inverses with an undergraduate-level understanding of linear algebra.Developments in Mathematics,1389-2177 ;53Matrix theoryAlgebraOperator theoryComputer scienceMathematicsLinear and Multilinear Algebras, Matrix Theoryhttps://scigraph.springernature.com/ontologies/product-market-codes/M11094Operator Theoryhttps://scigraph.springernature.com/ontologies/product-market-codes/M12139Computational Mathematics and Numerical Analysishttps://scigraph.springernature.com/ontologies/product-market-codes/M1400XMatrix theory.Algebra.Operator theory.Computer scienceMathematics.Linear and Multilinear Algebras, Matrix Theory.Operator Theory.Computational Mathematics and Numerical Analysis.512.5Wang Guorongauthttp://id.loc.gov/vocabulary/relators/aut767977Wei Yiminauthttp://id.loc.gov/vocabulary/relators/autQiao Sanzhengauthttp://id.loc.gov/vocabulary/relators/autMiAaPQMiAaPQMiAaPQBOOK9910300102803321Generalized Inverses: Theory and Computations2047135UNINA