03505nam 22005775 450 991025465800332120200706201156.03-319-53168-910.1007/978-3-319-53168-7(CKB)3710000001388507(DE-He213)978-3-319-53168-7(MiAaPQ)EBC4863574(PPN)201472090(EXLCZ)99371000000138850720170520d2017 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierCell Biology of Herpes Viruses /edited by Klaus Osterrieder1st ed. 2017.Cham :Springer International Publishing :Imprint: Springer,2017.1 online resource (VII, 224 p. 18 illus., 9 illus. in color.) Advances in Anatomy, Embryology and Cell Biology,0301-5556 ;2233-319-53167-0 Includes bibliographical references at the end of each chapters.Initial contact: The first steps in herpesvirus entry -- Herpesvirus capsid assembly and DNA packaging -- Interindividual spread of herpesviruses -- Innate immune mechanisms and herpes simplex virus infection and disease -- Herpesvirus latency. On the importance of positioning oneself -- The human CMV IE1 protein: An offender of PML nuclear bodies -- Assembly and egress of an alphaherpesvirus clockwork -- Herpes simplex virus membrane fusion. .Herpes viruses are widely distributed in nature, causing disease in organisms as diverse as bivalves and primates, including humans. Each virus appears to have established a long-standing relationship with its host, and the viruses have the ability to manipulate and control the metabolism of host cells, as well as innate and adaptive antiviral immune responses. Herpes viruses maintain themselves within hosts in a latent state resulting in virus persistence for years – usually for the life span of the hosts. Herpes viruses comprise a large number of pathogens with diverse cellular targets and biological consequences of infection. What they have in common is their structure and the fact that they establish a dormant (latent) infection in their hosts that usually persists for life. The reviews here will highlight the general principles of herpes virus infection, with equal attention to overall principle and important difference. Also, the cell type- and life-style dependent differences in the establishment and maintenance of virus persistence will be covered.Advances in Anatomy, Embryology and Cell Biology,0301-5556 ;223VirologyImmunologyCytologyVirologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B22003Immunologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B14000Cell Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L16008Virology.Immunology.Cytology.Virology.Immunology.Cell Biology.576.6484Osterrieder Klausedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910254658003321Cell Biology of Herpes Viruses1552000UNINA