03819nam 22006975 450 991025405100332120200630105418.0981-10-1486-810.1007/978-981-10-1486-4(CKB)3710000000732526(DE-He213)978-981-10-1486-4(MiAaPQ)EBC4557281(PPN)194376931(EXLCZ)99371000000073252620160614d2016 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierMechanism of Functional Expression of the Molecular Machines /by Masahiro Kinoshita1st ed. 2016.Singapore :Springer Singapore :Imprint: Springer,2016.1 online resource (X, 70 p. 30 illus., 24 illus. in color.)SpringerBriefs in Molecular Science,2191-5407981-10-1484-1 Includes bibliographical references at the end of each chapters.Introduction -- Importance of Translational, Configurational Entropy of Water -- Molecular Machines -- Concluding Remarks: Mechanism of Functional Expression Common in the Molecular Machines.This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules coexisting with the molecular machines in the entire system.SpringerBriefs in Molecular Science,2191-5407Physical chemistryBiophysicsBiological physicsProteins Statistical physicsDynamical systemsPhysical Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C21001Biological and Medical Physics, Biophysicshttps://scigraph.springernature.com/ontologies/product-market-codes/P27008Protein-Ligand Interactionshttps://scigraph.springernature.com/ontologies/product-market-codes/L14060Complex Systemshttps://scigraph.springernature.com/ontologies/product-market-codes/P33000Statistical Physics and Dynamical Systemshttps://scigraph.springernature.com/ontologies/product-market-codes/P19090Physical chemistry.Biophysics.Biological physics.Proteins .Statistical physics.Dynamical systems.Physical Chemistry.Biological and Medical Physics, Biophysics.Protein-Ligand Interactions.Complex Systems.Statistical Physics and Dynamical Systems.539.6Kinoshita Masahiroauthttp://id.loc.gov/vocabulary/relators/aut1059440MiAaPQMiAaPQMiAaPQBOOK9910254051003321Mechanism of Functional Expression of the Molecular Machines2505873UNINA