01278nam2 2200301 i 450 CFI011179120231121125437.0IT89-11538 19971223d1989 ||||0itac50 baitaitz01i xxxe z01n1Abadeh-CzakanL. Grassi, M. Pepe, G. SestieriTorinoUTET©1989VIII, 304 p., [36! c. di tav.ill.29 cm.001CFI01117862001 Dizionario di antiquariatoL. Grassi, M. Pepe, G. Sestieri1ITIT-0119971223IT-RM028 IT-FR0084 IT-RM1163 IT-FR0017 Biblioteca Universitaria AlessandrinaRM028 Biblioteca Del Monumento Nazionale Di MontecassinoFR0084 Istituto Centrale Restauro Conservazione Patrimonio Archivistico LibrarioRM1163 Biblioteca umanistica Giorgio ApreaFR0017 CFI0111791Biblioteca umanistica Giorgio Aprea 52S.L. 745.10 Diz.Ant.Gra.1 52FLS0000200425 VMN RS Vol. 1C 2012071820120718 01 25 36 52161339UNICAS04051nam 22006015 450 991025395730332120260810165416.03-319-68948-710.1007/978-3-319-68948-7(CKB)4100000001382014(DE-He213)978-3-319-68948-7(MiAaPQ)EBC5210136(PPN)222228121(EXLCZ)99410000000138201420171223d2017 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierMarburg- and Ebolaviruses From Ecosystems to Molecules /edited by Elke Mühlberger, Lisa L. Hensley, Jonathan S. Towner1st ed. 2017.Cham :Springer International Publishing :Imprint: Springer,2017.1 online resource (X, 460 p.) Current Topics in Microbiology and Immunology,2196-9965 ;4113-319-68946-0 Includes bibliographical references at the end of each chapters.Filovirus Research: How it began -- Ecology of Filoviruses -- West Africa 2013 Ebola: From Virus Outbreak to Humanitarian Crisis -- Clinical Management of Ebola Virus Disease Patients in Low Resource Settings -- Clinical Management of Patients with Ebola Virus Disease in High Resource Settings -- Ebola Virus Disease in Humans: Pathophysiology and Immunity -- Nonhuman Primate Models of Ebola Virus Disease -- Small Animal Models for Studying Filovirus Pathogenesis -- Accelerating Vaccine Development during the West African Ebola Virus Disease Outbreak -- Therapeutics against Filovirus Infection -- Filovirus Strategies to Escape Antiviral Responses -- Mechanisms of Filovirus Entry -- Inside the Cell: Assembly of Filoviruses -- Filovirus Structural Biology: The Molecules in the Machine -- Reverse Genetics of Filoviruses -- Guide to the Correct Use of Filoviral Nomenclature.This volume provides an overview of recent advances in our understanding of the biology of marburg- and ebolaviruses. It focuses on four essential areas: 1) ecology, outbreaks and clinical management, 2) disease, pathogenesis and protection, 3) virus replication inside the cell, and 4) molecular tools for virus study and taxonomy. For 50 years, these viruses have spilled over sporadically and without warning from their wildlife reservoirs, often causing major outbreaks and high fatalities. The consequences can be devastating, with a clear potential for global reach, as demonstrated by the 2013 West African outbreak of Ebola virus, which led to over 28,000 reported cases across three continents and more than 11,000 deaths. Given the international threat posed by these viruses, the pace and scope of basic research have also greatly intensified, ranging from studies of virus emergence, epidemiology, antiviral countermeasures and human disease to detailed mechanistic studies of virus entry, replication, virion assembly and protein structure. Written by internationally respected experts, this book will appeal to a wide audience and be a valuable resource for basic researchers, clinicians and advanced students alike.Current Topics in Microbiology and Immunology,2196-9965 ;411VirologyDiseasesEpidemiologyVirologyDiseasesEpidemiologyVirology.Diseases.Epidemiology.Virology.Diseases.Epidemiology.579.25Mühlberger Elke.edthttp://id.loc.gov/vocabulary/relators/edtHensley Lisa L.edthttp://id.loc.gov/vocabulary/relators/edtTowner Jonathan S.edthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910253957303321Marburg- and Ebolaviruses2233550UNINA