02903nam 22005295 450 991025393440332120200630164104.01-4939-7299-510.1007/978-1-4939-7299-9(CKB)4100000001040729(DE-He213)978-1-4939-7299-9(MiAaPQ)EBC5143921(PPN)221248374(EXLCZ)99410000000104072920171110d2017 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierGene and Cell Therapies for Beta-Globinopathies /edited by Punam Malik, John Tisdale1st ed. 2017.New York, NY :Springer New York :Imprint: Springer,2017.1 online resource (XII, 248 p. 16 illus., 12 illus. in color.) American Society of Gene & Cell Therapy,2626-7713 ;10131-4939-7297-9 Includes bibliographical references and index.This book provides a comprehensive review of gene and cell therapy approaches for hemoglobinopathies. It covers the progress and current state of the field in hematopoietic stem cell transplantation for hemoglobinopathies and genetic correction of autologous hematopoietic stem cells. Chapters focus on such topics as the current standards of care and long term outcomes of b-thalassemias and sickle cell disease, the ability to generate autologous embryonic stem cell-like cells from primary somatic cells, and genetic strategies to reactivate fetal hemoglobin production. In addition to offering a thorough review of the field in its present state, this book also sheds light on the major changes expected in coming years.   Gene and Cell Therapies for Beta-Globinopathies is part of the American Society of Gene and Cell Therapy sub-series of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students, clinicians, and researchers interested in gene and cell therapy.American Society of Gene & Cell Therapy,2626-7713 ;1013Gene therapyCytologyGene Therapyhttps://scigraph.springernature.com/ontologies/product-market-codes/B12020Cell Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L16008Gene therapy.Cytology.Gene Therapy.Cell Biology.616.151Malik Punamedthttp://id.loc.gov/vocabulary/relators/edtTisdale Johnedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910253934403321Gene and Cell Therapies for Beta-Globinopathies2234130UNINA