01110nam0 22002651i 450 UON0032916620231205104213.41520090826f |0itac50 baporPT|||| 1||||ˆA ‰tragédia de D. RamoncontosBranquinho da FonsecaLisboaEdiçao de fomento de publicações[19--?]47 p.17 cm.001UON003291672001 Mosaicopequena antologia de obras primas210 LisboaEdição de fomento publicações.PTLisboaUONL003135869.2Letteratura drammatica portoghese21Da FonsecaBranquinhoUONV187451700769Edição de fomento de publicaçõesUONV275891650ITSOL20240220RICASIBA - SISTEMA BIBLIOTECARIO DI ATENEOUONSIUON00329166SIBA - SISTEMA BIBLIOTECARIO DI ATENEOSI Port III 0032 SI SP 163 5 0032 Tragédia de D. Ramon1368188UNIOR04294nam 22006135 450 991025392030332120200630222240.0981-10-2579-710.1007/978-981-10-2579-2(CKB)4340000000062004(MiAaPQ)EBC4901229(DE-He213)978-981-10-2579-2(PPN)203667344(EXLCZ)99434000000006200420170705d2017 u| 0engurcnu||||||||rdacontentrdamediardacarrierCancer and Chemoprevention: An Overview /by Summya Rashid1st ed. 2017.Singapore :Springer Singapore :Imprint: Springer,2017.1 online resource (173 pages) illustrations (some color), tables981-10-2578-9 Includes bibliographical references at the end of each chapters.Introduction -- Hallmarks of Cancer -- Classification of Cancer -- Factors Influencing Cancer Development -- Carcinogenesis -- Molecular Mechanism of Carcinogenesis -- Oxidative Stress Induced Carcinogenesis -- Major Mediators Linking Inflammation and Cancer -- Apoptosis -- Chemoprevention -- Classification of Chemopreventive Agents -- Preclinical Development of Chemo Preventive Agents for Chemoprevention -- Modulation of Wnt/β-Catenin Signaling by Chemo Prevention -- Modulation of Akt/mTOR Pathway Signaling by Chemo Prevention -- Novel Chemopreventive Agents -- Chemoprevention by Resveratrol -- Chemoprevention by Genistein -- Chemoprevention by Apigenin -- Chemoprevention by Curcumin -- Chemoprevention by Fisetin -- Chemoprevention by Epigallocatechin-3-gallate (EGCG) -- Chemoprevention by Graviola -- Cancer Chemoprevention: Hurdles and Future Prospects and Considerations -- Clinical Trials of Chemoprevention -- Future of Chemoprevention.This book focuses on the most recent, relevant, comprehensive and significant advances in cancer and chemo prevention. It broadly discusses cancer, its hallmarks and classification, molecular mechanisms of outbreak, contributing factors, role of oxidative stress, inflammatory mediators and evading apoptosis, which leads to the progression of disease. Though modern medicine has left us with no option to treat this deadly disease due to drawbacks associated with conventional treatment – like its non-targeted nature, drug resistance, varied organ toxicities and unaffordability – chemoprevention offers a viable therapeutic window. Given chemoprevention’s importance in the present scenario, the book highlights various chemo preventive strategies currently used in the management of cancer; a selection of novel chemo preventive agents used at clinics and in the pre-clinical stage; hurdles to effective chemoprevention; future prospects and the road ahead. It offers a valuable guide for all graduate students and researchers seeking information on cancer and chemoprevention in general, irrespective of the specific type/pathways involved in its onset.CancerResearchApoptosisGene expressionCell cycleImmunologyCancer Researchhttps://scigraph.springernature.com/ontologies/product-market-codes/B11001Apoptosishttps://scigraph.springernature.com/ontologies/product-market-codes/L16060Gene Expressionhttps://scigraph.springernature.com/ontologies/product-market-codes/B12010Cell Cycle Analysishttps://scigraph.springernature.com/ontologies/product-market-codes/L16030Immunologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B14000CancerResearch.Apoptosis.Gene expression.Cell cycle.Immunology.Cancer Research.Apoptosis.Gene Expression.Cell Cycle Analysis.Immunology.616.99405Rashid Summyaauthttp://id.loc.gov/vocabulary/relators/aut979630BOOK9910253920303321Cancer and Chemoprevention: An Overview2234119UNINA