03835nam 22005535 450 991025390310332120200703210755.03-319-39406-110.1007/978-3-319-39406-0(CKB)3710000000838018(EBL)4654007(DE-He213)978-3-319-39406-0(MiAaPQ)EBC4654007(PPN)194804615(EXLCZ)99371000000083801820160824d2016 u| 0engur|n|---|||||txtrdacontentcrdamediacrrdacarrierApoptosis in Cancer Pathogenesis and Anti-cancer Therapy New Perspectives and Opportunities /edited by Christopher D. Gregory1st ed. 2016.Cham :Springer International Publishing :Imprint: Springer,2016.1 online resource (260 p.)Advances in Experimental Medicine and Biology,0065-2598 ;930Includes index.3-319-39404-5 Foreword -- Preface -- 1. Molecular Cell Biology of Apoptosis and Necroptosis in Cancer -- 2. Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis -- 3. Micro-environmental Effects of Cell Death in Malignant Disease -- 4. Apoptotic Caspases in Promoting Cancer: Implications from Their Roles in Development and Tissue Homeostasis -- 5. Axl and Mer Receptor Tyrosine Kinases: Distinct and Non-overlapping Roles in Inflammation and Cancer? -- 6. Immunogenic Apoptotic Cell Death and Anti-cancer Immunity -- 7. Cancer Cell Death-inducing Radiotherapy – Impact on Local Tumour Control, Tumour Cell Proliferation and Induction of Systemic Anti-tumour Immunity -- 8. Novel Approaches to Apoptosis-inducing Therapies -- 9. Killing Is Not Enough – How Apoptosis Hijacks Tumor-associated Macrophages to Promote Cancer Progression -- Index.This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.Advances in Experimental Medicine and Biology,0065-2598 ;930Cancer researchApoptosisMolecular biologyCancer Researchhttps://scigraph.springernature.com/ontologies/product-market-codes/B11001Apoptosishttps://scigraph.springernature.com/ontologies/product-market-codes/L16060Molecular Medicinehttps://scigraph.springernature.com/ontologies/product-market-codes/B1700XCancer research.Apoptosis.Molecular biology.Cancer Research.Apoptosis.Molecular Medicine.610Gregory Christopher Dedthttp://id.loc.gov/vocabulary/relators/edtBOOK9910253903103321Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy2517337UNINA