03776nam 22006615 450 991025388640332120200704112902.03-319-29556-X10.1007/978-3-319-29556-5(CKB)3710000000645549(EBL)4504388(SSID)ssj0001665627(PQKBManifestationID)16455005(PQKBTitleCode)TC0001665627(PQKBWorkID)14999881(PQKB)11358738(DE-He213)978-3-319-29556-5(MiAaPQ)EBC4504388(PPN)19344187X(EXLCZ)99371000000064554920160411d2016 u| 0engur|n|---|||||txtccrHistophilus somni Biology, Molecular Basis of Pathogenesis, and Host Immunity /edited by Thomas J. Inzana1st ed. 2016.Cham :Springer International Publishing :Imprint: Springer,2016.1 online resource (165 p.)Current Topics in Microbiology and Immunology,0070-217X ;396Description based upon print version of record.3-319-29554-3 Includes bibliographical references at the end of each chapters.Taxonomy of Histophilus somni -- Histophilosis as a Natural Disease -- Histophilus somni Genomics and Genetics -- Interactions on Histophilus somni with Host Cells -- Histophilus somni Surface Proteins -- Host Immune Response to Histophilus somni -- The Many Facets of Lipooligosaccharide as a Virulence Factor of Histophilus somni -- Exopolysaccharide Production and Biofilm Formation by Histophilus somni.This volume reviews the current understanding of the taxonomy, disease syndromes, genetics, biology, and pathogenic factors of Histophilus somni, as well as the host immune response to this pathogen. H. somni is one of the most important bacterial pathogens in cattle and other ruminants, and its virulence factors are highly conserved with Haemophilus influenzae and other members of the Pasteurellaceae. H. somni has been recognized as a major cause of thrombotic meningoencephalitis, respiratory disease syndromes, myocarditis, reproductive disease syndromes, polyarthritis, mastitis, ocular disease, and septicemia. The only known habitats of H. somni are the mucosal surfaces of ruminants, making this bacterium an opportunistic pathogen. Although it is capable of causing inflammation at systemic sites and is toxic to epithelial and phagocytic cells, the bacterium’s wide array of virulence factors act primarily as a defense against, or to escape recognition from, host innate and adaptive immunity.Current Topics in Microbiology and Immunology,0070-217X ;396Medical microbiologyVeterinary medicineBacteriologyMedical Microbiologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B16003Veterinary Medicine/Veterinary Sciencehttps://scigraph.springernature.com/ontologies/product-market-codes/H67000Bacteriologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L23012Medical microbiology.Veterinary medicine.Bacteriology.Medical Microbiology.Veterinary Medicine/Veterinary Science.Bacteriology.636.0896014Inzana Thomas Jedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910253886403321Histophilus somni2527582UNINA